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Luis Sanchez-Pulido

Explore the profile of Luis Sanchez-Pulido including associated specialties, affiliations and a list of published articles. Areas
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Articles 68
Citations 3151
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Recent Articles
1.
Saredi G, Carelli F, Rolland S, Furlan G, Piquet S, Appert A, et al.
Nat Struct Mol Biol . 2024 Jan; 31(3):523-535. PMID: 38238586
Histone chaperones control nucleosome density and chromatin structure. In yeast, the H3-H4 chaperone Spt2 controls histone deposition at active genes but its roles in metazoan chromatin structure and organismal physiology...
2.
Rios-Szwed D, Alvarez V, Sanchez-Pulido L, Garcia-Wilson E, Jiang H, Bandau S, et al.
Life Sci Alliance . 2023 Oct; 6(12). PMID: 37793778
FAM111A is a replisome-associated protein and dominant mutations within its trypsin-like peptidase domain are linked to severe human developmental syndrome, the Kenny-Caffey syndrome. However, FAM111A functions remain unclear. Here, we...
3.
Sanchez-Pulido L, Jia S, Hansen C, Ponting C
Bioinform Adv . 2023 Jan; 2(1):vbac008. PMID: 36699391
Motivation: Disrupted gene expression causes an intractable congenital diarrhoea in infants. However, this gene's molecular mechanism is unknown and no homologous proteins have been reported. Results: Our detailed evolutionary analysis...
4.
Sanchez-Pulido L, Ponting C
Bioinform Adv . 2023 Jan; 2(1):vbac087. PMID: 36699367
Summary: The 10 known BRICHOS domain-containing proteins in humans have been linked to an unusually long list of pathologies, including cancer, obesity and two amyloid-like diseases. BRICHOS domains themselves have...
5.
Zaffar E, Ferreira P, Sanchez-Pulido L, Boos D
Biology (Basel) . 2022 Jun; 11(6). PMID: 35741348
The initiation step of replication at replication origins determines when and where in the genome replication machines, replisomes, are generated. Tight control of replication initiation helps facilitate the two main...
6.
Ferreira P, Sanchez-Pulido L, Marko A, Ponting C, Boos D
Life Sci Alliance . 2022 Jan; 5(5). PMID: 35091422
Faithful genome duplication requires appropriately controlled replication origin firing. The metazoan origin firing regulation hub Treslin/TICRR and its yeast orthologue Sld3 share the Sld3-Treslin domain and the adjacent TopBP1/Dpb11 interaction...
7.
Cummings T, Gori K, Sanchez-Pulido L, Gavriilidis G, Moi D, Wilson A, et al.
Mol Biol Evol . 2021 Nov; 39(2). PMID: 34730808
Protein posttranslational modifications add great sophistication to biological systems. Citrullination, a key regulatory mechanism in human physiology and pathophysiology, is enigmatic from an evolutionary perspective. Although the citrullinating enzymes peptidylarginine...
8.
Sanchez-Pulido L, Ponting C
J Mol Biol . 2021 Jun; 433(20):167106. PMID: 34139218
Traditional sequence analysis algorithms fail to identify distant homologies when they lie beyond a detection horizon. In this review, we discuss how co-evolution-based contact and distance prediction methods are pushing...
9.
Findlay A, McKie L, Keighren M, Clementson-Mobbs S, Sanchez-Pulido L, Wells S, et al.
Sci Rep . 2020 Jan; 10(1):437. PMID: 31949211
Fam151b is a mammalian homologue of the C. elegans menorin gene, which is involved in neuronal branching. The International Mouse Phenotyping Consortium (IMPC) aims to knock out every gene in...
10.
Sanchez-Pulido L, Ponting C
Bioinformatics . 2019 Sep; 36(4):990-993. PMID: 31562761
Summary: CPLANE is a protein complex required for assembly and maintenance of primary cilia. It contains several proteins, such as INTU, FUZ, WDPCP, JBTS17 and RSG1 (REM2- and RAB-like small...