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Luis M S Loura

Explore the profile of Luis M S Loura including associated specialties, affiliations and a list of published articles. Areas
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Articles 78
Citations 836
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Recent Articles
1.
Cardoso R, Lairion F, Disalvo E, Loura L, Moreno M
Molecules . 2025 Jan; 29(24. PMID: 39769931
The membrane dipole potential that arises from the interfacial water and constitutive dipolar groups of lipid molecules modulates the interaction of amphiphiles and proteins with membranes. Consequently, its determination for...
2.
Oliveira A, Filipe H, Geraldes C, Voth G, Moreno M, Loura L
Inorg Chem . 2024 May; 63(24):10897-10914. PMID: 38795015
Contrast agents are important imaging probes in clinical MRI, allowing the identification of anatomic changes that otherwise would not be possible. Intensive research on the development of new contrast agents...
3.
Varandas P, Belinha R, Cobb A, Ramalho J, Segundo M, Loura L, et al.
Biochim Biophys Acta Biomembr . 2024 May; 1866(7):184335. PMID: 38763271
A series of phosphatidylethanolamine fluorescent probes head-labelled with 3-carboxycoumarin was prepared by an improved bioconjugation approach through continuous flow synthesis. The established procedure, supported by a design of experiment (DoE)...
4.
Moran-Lalangui M, Coutinho A, Prieto M, Fedorov A, Perez-Gil J, Loura L, et al.
Protein Sci . 2023 Nov; 33(1):e4835. PMID: 37984447
Pulmonary surfactant (PS) is a lipid-protein complex that forms films reducing surface tension at the alveolar air-liquid interface. Surfactant protein C (SP-C) plays a key role in rearranging the lipids...
5.
Cordeiro M, Filipe H, Dos Santos P, Samelo J, Ramalho J, Loura L, et al.
Molecules . 2023 Aug; 28(15). PMID: 37570608
Hoechst 33342 (H33342) is a fluorescent probe that is commonly used to stain the DNA of living cells. To do so, it needs to interact with and permeate through cell...
6.
Filipe H, Loura L, Moreno M
Membranes (Basel) . 2023 Jun; 13(6). PMID: 37367755
Permeation through biomembranes is ubiquitous for drugs to reach their active sites. Asymmetry of the cell plasma membrane (PM) has been described as having an important role in this process....
7.
Oliveira A, Filipe H, Loura L
Molecules . 2023 Mar; 28(5). PMID: 36903487
Fluorescence probes are indispensable tools in biochemical and biophysical membrane studies. Most of them possess extrinsic fluorophores, which often constitute a source of uncertainty and potential perturbation to the host...
8.
Moreno M, Filipe H, Cunha S, Ramos C, Martins P, Abel B, et al.
Pharmaceutics . 2023 Jan; 15(1). PMID: 36678803
The transport of drugs by efflux transporters in biomembranes limits their bioavailability and is a major determinant of drug resistance development by cancer cells and pathogens. A large number of...
9.
Moreno M, Loura L, Martins J, Salvador A, Velazquez-Campoy A
Int J Mol Sci . 2022 Sep; 23(17). PMID: 36077155
The equilibrium distribution of small molecules (ligands) between binding agents in heterogeneous media is an important property that determines their activity. Heterogeneous systems containing proteins and lipid membranes are particularly...
10.
Oliveira A, Filipe H, Ramalho J, Salvador A, Geraldes C, Moreno M, et al.
Inorg Chem . 2022 Jul; 61(30):11837-11858. PMID: 35849762
The correct parametrization of lanthanide complexes is of the utmost importance for their characterization using computational tools such as molecular dynamics simulations. This allows the optimization of their properties for...