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Ana Coutinho

Explore the profile of Ana Coutinho including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 337
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Recent Articles
1.
Millette M, Coutinho A, Prieto M, Salesse C
Biochemistry . 2025 Feb; 64(5):987-1005. PMID: 39977231
Membrane binding of monotopic proteins can involve various post-translational modifications or a combination of some membrane-binding elements. For example, amphipathic α helices and palmitoylation could drive the membrane attachment of...
2.
Coutinho A, Poveda J, Renart M
Methods Mol Biol . 2024 Jun; 2796:35-72. PMID: 38856894
Fluorescence techniques have been widely used to shed light over the structure-function relationship of potassium channels for the last 40-50 years. In this chapter, we describe how a Förster resonance...
3.
da Rocha M, Saint Aroman M, Mengeaud V, Carballido F, Doat G, Coutinho A, et al.
Int J Womens Health . 2024 Apr; 16:663-678. PMID: 38650835
Previously considered a skin disease exclusively affecting adolescents, characterized by inflammatory and non-inflammatory skin lesions, acne vulgaris is now increasingly observed in adult life, including post-menopause. Today, adult female acne...
4.
Lopes-Nunes J, Simoes P, Moreira D, Leandro K, Nobre R, de Almeida L, et al.
Int J Biol Macromol . 2024 Jan; 259(Pt 2):129157. PMID: 38199539
Oral cancer incidence and mortality are increasing over time. The most common therapies for oral cancers are surgery and radiotherapy, either used alone or combined, and immunotherapy can be also...
5.
Moran-Lalangui M, Coutinho A, Prieto M, Fedorov A, Perez-Gil J, Loura L, et al.
Protein Sci . 2023 Nov; 33(1):e4835. PMID: 37984447
Pulmonary surfactant (PS) is a lipid-protein complex that forms films reducing surface tension at the alveolar air-liquid interface. Surfactant protein C (SP-C) plays a key role in rearranging the lipids...
6.
Dias S, Pinto S, Silva-Herdade A, Cavaco M, Neves V, Tavares L, et al.
ACS Infect Dis . 2023 Sep; 9(10):1889-1900. PMID: 37669146
The formation of biofilms is a common virulence factor that makes bacterial infections difficult to treat and a major human health problem. Biofilms are bacterial communities embedded in a self-produced...
7.
Silva Cunha P, Antunes D, Laranjo S, Coutinho A, Abecasis J, Oliveira M
Front Cardiovasc Med . 2023 Jun; 10:1149717. PMID: 37363091
Early-onset atrial fibrillation (AF) can be the manifestation of a genetic atrial myopathy. However, specific genetic identification of a mutation causing atrial fibrosis is rare. We report a case of...
8.
Dias S, Pinto S, Silva-Herdade A, Cheneval O, Craik D, Coutinho A, et al.
J Antimicrob Chemother . 2022 Sep; 77(12):3256-3264. PMID: 36171717
Background: Infections caused by bacterial biofilms are very difficult to treat. The use of currently approved antibiotics even at high dosages often fails, making the treatment of these infections very...
9.
Giudici A, Renart M, Coutinho A, Morales A, Gonzalez-Ros J, Poveda J
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012519
Y55W mutants of non-selective NaK and partly K-selective NaK2K channels have been used to explore the conformational dynamics at the pore region of these channels as they interact with either...
10.
Borges-Araujo L, Monteiro M, Mil-Homens D, Bernardes N, Sarmento M, Coutinho A, et al.
Biomolecules . 2022 Jul; 12(7). PMID: 35883468
Despite its low abundance, phosphatidylinositol 4,5-bisphosphate (PI(4,5)P) is a key modulator of membrane-associated signaling events in eukaryotic cells. Temporal and spatial regulation of PI(4,5)P concentration can achieve localized increases in...