Hugo A L Filipe
Overview
Explore the profile of Hugo A L Filipe including associated specialties, affiliations and a list of published articles.
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26
Citations
227
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Recent Articles
1.
Oliveira A, Filipe H, Geraldes C, Voth G, Moreno M, Loura L
Inorg Chem
. 2024 May;
63(24):10897-10914.
PMID: 38795015
Contrast agents are important imaging probes in clinical MRI, allowing the identification of anatomic changes that otherwise would not be possible. Intensive research on the development of new contrast agents...
2.
Cordeiro M, Filipe H, Dos Santos P, Samelo J, Ramalho J, Loura L, et al.
Molecules
. 2023 Aug;
28(15).
PMID: 37570608
Hoechst 33342 (H33342) is a fluorescent probe that is commonly used to stain the DNA of living cells. To do so, it needs to interact with and permeate through cell...
3.
Filipe H, Moreira A, Miguel S, Ribeiro M, Coutinho P
Pharmaceutics
. 2023 Jul;
15(7).
PMID: 37514039
Cancer is considered a major societal challenge for the next decade worldwide. Developing strategies for simultaneous diagnosis and treatment has been considered a promising tool for fighting cancer. For this,...
4.
Filipe H, Loura L, Moreno M
Membranes (Basel)
. 2023 Jun;
13(6).
PMID: 37367755
Permeation through biomembranes is ubiquitous for drugs to reach their active sites. Asymmetry of the cell plasma membrane (PM) has been described as having an important role in this process....
5.
Duarte A, Costa E, Filipe H, Saraiva S, Jacinto T, Miguel S, et al.
Biomater Adv
. 2023 May;
151:213428.
PMID: 37146527
More than fifty years after the 3Rs definition and despite the continuous implementation of regulatory measures, animals continue to be widely used in basic research. Their use comprises not only...
6.
Oliveira A, Filipe H, Loura L
Molecules
. 2023 Mar;
28(5).
PMID: 36903487
Fluorescence probes are indispensable tools in biochemical and biophysical membrane studies. Most of them possess extrinsic fluorophores, which often constitute a source of uncertainty and potential perturbation to the host...
7.
Moreno M, Filipe H, Cunha S, Ramos C, Martins P, Abel B, et al.
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678803
The transport of drugs by efflux transporters in biomembranes limits their bioavailability and is a major determinant of drug resistance development by cancer cells and pathogens. A large number of...
8.
Oliveira A, Filipe H, Ramalho J, Salvador A, Geraldes C, Moreno M, et al.
Inorg Chem
. 2022 Jul;
61(30):11837-11858.
PMID: 35849762
The correct parametrization of lanthanide complexes is of the utmost importance for their characterization using computational tools such as molecular dynamics simulations. This allows the optimization of their properties for...
9.
Filipe H, Loura L
Molecules
. 2022 Apr;
27(7).
PMID: 35408504
Molecular dynamics (MD) simulations have led to great advances in many scientific disciplines, such as chemical physics, materials science, and biophysics [...].
10.
Magalhaes N, Simoes G, Ramos C, Samelo J, Oliveira A, Filipe H, et al.
Molecules
. 2022 Feb;
27(4).
PMID: 35209208
Background: rhodamines are dyes widely used as fluorescent tags in cell imaging, probing of mitochondrial membrane potential, and as P-glycoprotein model substrates. In all these applications, detailed understanding of the...