Luis M Gutierrez
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Explore the profile of Luis M Gutierrez including associated specialties, affiliations and a list of published articles.
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44
Citations
668
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Recent Articles
1.
Villanueva J, Gimenez-Molina Y, Gutierrez L
Methods Mol Biol
. 2022 Oct;
2565:297-309.
PMID: 36205902
Cultured bovine chromaffin cells have been characterized as a successful model to study changes in the cytoskeleton during the secretory process. In this sense, the distribution and dynamics of the...
2.
Villanueva J, Gimenez-Molina Y, Davletov B, Gutierrez L
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163009
The fusion of membranes is a central part of the physiological processes involving the intracellular transport and maturation of vesicles and the final release of their contents, such as neurotransmitters...
3.
Gimenez-Molina Y, Garcia-Martinez V, Villanueva J, Davletov B, Gutierrez L
Sci Rep
. 2019 Dec;
9(1):18471.
PMID: 31804600
FTY-720 (Fingolimod) was one of the first compounds authorized for the treatment of multiple sclerosis. Among its other activities, this sphingosine analogue enhances exocytosis in neuroendocrine chromaffin cells, altering the...
4.
Gimenez-Molina Y, Villanueva J, Frances M, Viniegra S, Gutierrez L
Front Cell Neurosci
. 2018 Oct;
12:344.
PMID: 30356839
Neuroendocrine chromaffin cells represent an excellent model to study the molecular mechanisms associated with the exo-endocytotic cycle of neurotransmitter release. In this study, EGFP-Lifeact and confocal microscopy has been used...
5.
Villanueva J, Gimenez-Molina Y, Gutierrez L
Methods Mol Biol
. 2018 Oct;
1860:379-389.
PMID: 30317519
Cultured bovine chromaffin cells have been tested as a successful neuroendocrine model to study the secretory process. Changes in the dynamics of the secretory vesicles and the exocytotic machinery microdomains...
6.
Felix-Martinez G, Gil A, Segura J, Villanueva J, Gutierrez L
Comput Biol Med
. 2018 Jul;
100:165-175.
PMID: 30015013
Catecholamines secretion from chromaffin cells is mediated by a Ca-dependent process in the submembrane space where the exocytotic machinery is located and high-Ca microdomains (HCMDs) are formed by the coordinated...
7.
Garcia-Martinez V, Gimenez-Molina Y, Villanueva J, Darios F, Davletov B, Gutierrez L
FEBS Lett
. 2018 Jul;
592(21):3493-3503.
PMID: 29962039
Membrane fusion is a key event in exocytosis of neurotransmitters and hormones stored in intracellular vesicles. In this process, soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) proteins are essential...
8.
Gutierrez L, Villanueva J
Pflugers Arch
. 2017 Jul;
470(1):181-186.
PMID: 28730385
Actin is one of the most ubiquitous protein playing fundamental roles in a variety of cellular processes. Since early in the 1980s, it was evident that filamentous actin (F-actin) formed...
9.
Darios F, Jorgacevski J, Flasker A, Zorec R, Garcia-Martinez V, Villanueva J, et al.
Sci Rep
. 2017 Jul;
7(1):5958.
PMID: 28729700
Neurotransmission and secretion of hormones involve a sequence of protein/lipid interactions with lipid turnover impacting on vesicle trafficking and ultimately fusion of secretory vesicles with the plasma membrane. We previously...
10.
Gimenez-Molina Y, Villanueva J, Nanclares C, Lopez-Font I, Viniegra S, Frances M, et al.
Front Cell Neurosci
. 2017 May;
11:135.
PMID: 28522964
Cultured bovine chromaffin cells have been used extensively as a neuroendocrine model to study regulated secretion. In order to extend such experimental findings to the physiological situation, it is necessary...