Ludovica Marando
Overview
Explore the profile of Ludovica Marando including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
469
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Recent Articles
1.
Kusne Y, Badar T, Lasho T, Marando L, Mangaonkar A, Finke C, et al.
Br J Haematol
. 2025 Mar;
PMID: 40040251
Germline variants in DDX41 (DDX41-germline predisposition syndrome [GPS]) are associated with predisposition to haematological malignancies (HM), including lymphoid and myeloid neoplasms (MN). We retrospectively analysed the clinical and molecular features...
2.
Marando L, Csizmar C, Patnaik M
Haematologica
. 2024 Oct;
110(1):22-36.
PMID: 39415698
Chronic myelomonocytic leukemia (CMML) is an aggressive clonal stem cell disorder categorized among myelodysplastic/ myeloproliferative overlap neoplasms. While sharing features with both myelodysplastic syndromes and myeloproliferative neoplasms, CMML has distinct...
3.
Kusne Y, Badar T, Lasho T, Ferrer A, Mangaonkar A, Finke C, et al.
Leuk Res
. 2024 Aug;
145:107561.
PMID: 39182344
No abstract available.
4.
Isobe T, Kucinski I, Barile M, Wang X, Hannah R, Bastos H, et al.
Cell Genom
. 2023 Dec;
3(12):100426.
PMID: 38116120
Acute myeloid leukemia (AML) and myeloid neoplasms develop through acquisition of somatic mutations that confer mutation-specific fitness advantages to hematopoietic stem and progenitor cells. However, our understanding of mutational effects...
5.
Gu M, Kovilakam S, Dunn W, Marando L, Barcena C, Mohorianu I, et al.
Nat Genet
. 2023 Sep;
55(10):1777.
PMID: 37726541
No abstract available.
6.
Gu M, Kovilakam S, Dunn W, Marando L, Barcena C, Mohorianu I, et al.
Nat Genet
. 2023 Aug;
55(9):1523-1530.
PMID: 37620601
The myeloid neoplasms encompass acute myeloid leukemia, myelodysplastic syndromes and myeloproliferative neoplasms. Most cases arise from the shared ancestor of clonal hematopoiesis (CH). Here we analyze data from 454,340 UK...
7.
Kovilakam S, Gu M, Dunn W, Marando L, Barcena C, Nik-Zainal S, et al.
Blood
. 2023 Jul;
142(14):1185-1192.
PMID: 37506341
Germ line variants in the DDX41 gene have been linked to myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) development. However, the risks associated with different variants remain unknown, as...
8.
Meduri E, Breeze C, Marando L, Richardson S, Huntly B
iScience
. 2022 Dec;
25(12):105622.
PMID: 36465109
Several studies have documented aberrant RNA editing patterns across multiple tumors across large patient cohorts from The Cancer Genome Atlas (TCGA). However, studies on understanding the role of RNA editing...
9.
Dawson M, Borthakur G, Huntly B, Karadimitris A, Alegre A, Chaidos A, et al.
Clin Cancer Res
. 2022 Nov;
29(4):711-722.
PMID: 36350312
Purpose: Molibresib is a selective, small molecule inhibitor of the bromodomain and extra-terminal (BET) protein family. This was an open-label, two-part, Phase I/II study investigating molibresib monotherapy for the treatment...
10.
Yun H, Narayan N, Vohra S, Giotopoulos G, Mupo A, Madrigal P, et al.
Nat Genet
. 2021 Sep;
53(10):1443-1455.
PMID: 34556857
Altered transcription is a cardinal feature of acute myeloid leukemia (AML); however, exactly how mutations synergize to remodel the epigenetic landscape and rewire three-dimensional DNA topology is unknown. Here, we...