Ludmila Kaplun
Overview
Explore the profile of Ludmila Kaplun including associated specialties, affiliations and a list of published articles.
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15
Citations
577
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Recent Articles
1.
Poliakov E, Kaplun L, Rogozin I
Front Genet
. 2024 Apr;
15:1384584.
PMID: 38572417
No abstract available.
2.
Kaplun L, Krautz-Peterson G, Neerman N, Stanley C, Hussey S, Folwick M, et al.
Front Genet
. 2023 May;
14:1145285.
PMID: 37152986
Technological advances in Next-Generation Sequencing dramatically increased clinical efficiency of genetic testing, allowing detection of a wide variety of variants, from single nucleotide events to large structural aberrations. Whole Genome...
3.
Turingan R, Brown J, Kaplun L, Smith J, Watson J, Boyd D, et al.
Int J Legal Med
. 2019 Nov;
134(3):863-872.
PMID: 31781850
Rapid identification of human remains following mass casualty events is essential to bring closure to family members and friends of the victims. Unfortunately, disaster victim identification, missing persons identification, and...
4.
Turingan R, Kaplun L, Krautz-Peterson G, Norsworthy S, Zolotova A, Joseph S, et al.
PLoS One
. 2017 Jun;
12(5):e0178653.
PMID: 28562672
Nucleic acid amplification tests (NAATs) are recommended by the CDC for detection of Chlamydia trachomatis (Ct) urogenital infections. Current commercial NAATs require technical expertise and sophisticated laboratory infrastructure, are time-consuming...
5.
Ramakrishnan G, Davaakhuu G, Kaplun L, Chung W, Rana A, Atfi A, et al.
J Biol Chem
. 2014 Jan;
289(9):6054-66.
PMID: 24446434
AKT/PKB kinases transmit insulin and growth factor signals downstream of phosphatidylinositol 3-kinase (PI3K). AKT activation involves phosphorylation at two residues, Thr(308) and Ser(473), mediated by PDK1 and the mammalian target...
6.
Kaplun L, Fridman A, Chen W, Levin N, Ahsan S, Petrucelli N, et al.
Biomark Insights
. 2013 Jan;
7:151-7.
PMID: 23300341
A substantial fraction of familial ovarian cancer cases cannot be attributed to specific genetic factors. The discovery of additional susceptibility genes will permit a more accurate assessment of hereditary cancer...
7.
Dobson M, Ramakrishnan G, Ma S, Kaplun L, Balan V, Fridman R, et al.
Biochim Biophys Acta
. 2011 May;
1813(8):1453-64.
PMID: 21621563
FoxO3 is a member of FoxO family transcription factors that mediate cellular functions downstream of AKT. FoxO3 phosphorylation by AKT generates binding sites for 14-3-3, which in-turn regulates FoxO3 transcriptional...
8.
Balan V, Miller G, Kaplun L, Balan K, Chong Z, Li F, et al.
J Biol Chem
. 2008 Aug;
283(41):27810-27819.
PMID: 18678867
The life span of model organisms can be modulated by environmental conditions that influence cellular metabolism, oxidation, or DNA integrity. The yeast nicotinamidase gene pnc1 was identified as a key...
9.
Leicht D, Balan V, Kaplun A, Singh-Gupta V, Kaplun L, Dobson M, et al.
Biochim Biophys Acta
. 2007 Jun;
1773(8):1196-212.
PMID: 17555829
The Ras-Raf-MAPK pathway regulates diverse physiological processes by transmitting signals from membrane based receptors to various nuclear, cytoplasmic and membrane-bound targets, coordinating a large variety of cellular responses. Function of...
10.
Vyazmensky M, Engel S, Kryukov O, Berkovich-Berger D, Kaplun L
Biochim Biophys Acta
. 2006 Jun;
1764(5):955-960.
PMID: 16795146
Acetohydroxyacid synthase I (AHAS I), one of three isozymes in Escherichia coli catalyzing the first common step in the biosynthesis of branched amino acids, is composed of two kinds of...