Guri Tzivion
Overview
Explore the profile of Guri Tzivion including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1537
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0
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Recent Articles
1.
Das S, Sondarva G, Viswakarma N, Nair R, Osipo C, Tzivion G, et al.
J Biol Chem
. 2015 Jul;
290(35):21705-12.
PMID: 26152725
Human epidermal growth factor receptor 2 (HER2) is amplified in ∼ 15-20% of human breast cancer and is important for tumor etiology and therapeutic options of breast cancer. Up-regulation of...
2.
Zhang M, Ferrigno O, Wang Z, Ohnishi M, Prunier C, Levy L, et al.
Cancer Cell
. 2015 Apr;
27(4):547-60.
PMID: 25873176
Many types of human cancers having hyperactivated Wnt signaling display no causative alterations in known effectors of this pathway. Here, we report a function of TGIF in Wnt signaling. TGIF...
3.
Brennan G, Jimenez-Mateos E, Sanz-Rodriguez A, Mooney C, Tzivion G, Henshall D, et al.
J Mol Neurosci
. 2015 Apr;
56(2):255-62.
PMID: 25854777
Recent studies demonstrated that overexpression of the molecular chaperone 14-3-3ζ protects the brain against endoplasmic reticulum (ER) stress and prolonged seizures. The 14-3-3 targets responsible for improved neuronal survival after...
4.
Ramakrishnan G, Davaakhuu G, Chung W, Zhu H, Rana A, Filipovic A, et al.
Sci Rep
. 2015 Mar;
5:8782.
PMID: 25740432
Members of the Notch family of transmembrane receptors, Notch1-4 in mammals, are involved in the regulation of cell fate decisions and cell proliferation in various organisms. The Notch4 isoform, which...
5.
Prunier C, Zhang M, Kumar S, Levy L, Ferrigno O, Tzivion G, et al.
Cell Rep
. 2015 Feb;
10(6):883-890.
PMID: 25683711
PHRF1 functions as an essential component of the TGF-β tumor suppressor pathway by triggering degradation of the homeodomain repressor factor TGIF. This leads to redistribution of cPML into the cytoplasm,...
6.
Dhar S, Kumar A, Li K, Tzivion G, Levenson A
Biochim Biophys Acta
. 2014 Dec;
1853(2):265-75.
PMID: 25447541
Metastasis associated protein 1 (MTA1) is a component of the nucleosome remodeling and deacetylating (NuRD) complex which mediates gene silencing and is overexpressed in several cancers. We reported earlier that...
7.
Ramakrishnan G, Davaakhuu G, Kaplun L, Chung W, Rana A, Atfi A, et al.
J Biol Chem
. 2014 Jan;
289(9):6054-66.
PMID: 24446434
AKT/PKB kinases transmit insulin and growth factor signals downstream of phosphatidylinositol 3-kinase (PI3K). AKT activation involves phosphorylation at two residues, Thr(308) and Ser(473), mediated by PDK1 and the mammalian target...
8.
Leicht D, Balan V, Zhu J, Kaplun A, Bronisz A, Rana A, et al.
Biochim Biophys Acta
. 2013 Jan;
1833(5):976-86.
PMID: 23360980
C-Raf is a member of the Ras-Raf-MEK-ERK mitogen-activated protein kinase (MAPK) signaling pathway that plays key roles in diverse physiological processes and is upregulated in many human cancers. C-Raf activation...
9.
Brennan G, Jimenez-Mateos E, McKiernan R, Engel T, Tzivion G, Henshall D
PLoS One
. 2013 Jan;
8(1):e54491.
PMID: 23359526
14-3-3 proteins are ubiquitous molecular chaperones that are abundantly expressed in the brain where they regulate cell functions including metabolism, the cell cycle and apoptosis. Brain levels of several 14-3-3...
10.
Rangasamy V, Mishra R, Sondarva G, Das S, Lee T, Bakowska J, et al.
Proc Natl Acad Sci U S A
. 2012 May;
109(21):8149-54.
PMID: 22566623
Nuclear protein peptidyl-prolyl isomerase Pin1-mediated prolyl isomerization is an essential and novel regulatory mechanism for protein phosphorylation. Therefore, tight regulation of Pin1 localization and catalytic activity is crucial for its...