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Lucile P A Neyton

Explore the profile of Lucile P A Neyton including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 42
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Recent Articles
1.
Zalucky A, Dianti J, Neyton L, Sinha P, Liu K, Matthay M, et al.
Am J Respir Crit Care Med . 2025 Feb; PMID: 39998496
Rationale: Patients with acute respiratory distress syndrome (ARDS) have a reduction in functional lung volume resulting in increased respiratory system elastance (Ers); however, the extent of this increase varies by...
2.
Neyton L, Patel R, Sarma A, Willmore A, Haller S, Kangelaris K, et al.
Nat Commun . 2024 Jun; 15(1):5483. PMID: 38942804
Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood....
3.
Valda Toro P, Willmore A, Wu N, Delucchi K, Jauregui A, Sinha P, et al.
Crit Care . 2024 Apr; 28(1):132. PMID: 38649920
Background: Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hypoxemia improves within 24 h after initiation of mechanical ventilation. Detailed clinical and...
4.
Neyton L, Sinha P, Sarma A, Mick E, Kalantar K, Chen S, et al.
Am J Respir Crit Care Med . 2024 Jan; 209(7):805-815. PMID: 38190719
Two molecular phenotypes of sepsis and acute respiratory distress syndrome, termed hyperinflammatory and hypoinflammatory, have been consistently identified by latent class analysis in numerous cohorts, with widely divergent clinical outcomes...
5.
Neyton L, Patel R, Sarma A, Willmore A, Haller S, Kangelaris K, et al.
Res Sq . 2023 Aug; PMID: 37577607
Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood....
6.
Hayes A, Zheng X, OKelly J, Neyton L, Bochkina N, Uings I, et al.
Cell Rep . 2023 Jul; 42(8):112763. PMID: 37478012
Kynurenine monooxygenase (KMO) blockade protects against multiple organ failure caused by acute pancreatitis (AP), but the link between KMO and systemic inflammation has eluded discovery until now. Here, we show...
7.
Neyton L, Langelier C, Calfee C
Crit Care . 2023 Mar; 27(1):90. PMID: 36941644
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2023. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2023 . Further...
8.
Neyton L, Zheng X, Skouras C, Doeschl-Wilson A, Gutmann M, Uings I, et al.
Ann Surg . 2020 Jun; 275(2):e453-e462. PMID: 32487804
Objective: Acute Pancreatitis (AP) is sudden onset pancreas inflammation that causes systemic injury with a wide and markedly heterogeneous range of clinical consequences. Here, we hypothesized that this observed clinical...
9.
Baillie J, Bretherick A, Haley C, Clohisey S, Gray A, Neyton L, et al.
PLoS Comput Biol . 2018 Mar; 14(3):e1005934. PMID: 29494619
Genetic variants underlying complex traits, including disease susceptibility, are enriched within the transcriptional regulatory elements, promoters and enhancers. There is emerging evidence that regulatory elements associated with particular traits or...