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Lucie Poppova

Explore the profile of Lucie Poppova including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 90
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Recent Articles
1.
Poppova L, Pavlova S, Gonzalez B, Kotaskova J, Plevova K, Dumbovic G, et al.
Epigenetics . 2022 Mar; 17(12):1628-1635. PMID: 35333703
Genome methylation profiles define naïve-like (n-CLL), memory-like (m-CLL), and intermediate (i-CLL) subsets of chronic lymphocytic leukaemia (CLL). The profiles can be easily determined by the analysis of the five-CpG signature....
2.
Janovska P, Verner J, Kohoutek J, Bryjova L, Gregorova M, Dzimkova M, et al.
Blood . 2018 Jan; 131(11):1206-1218. PMID: 29317454
Casein kinase 1δ/ε (CK1δ/ε) is a key component of noncanonical Wnt signaling pathways, which were shown previously to drive pathogenesis of chronic lymphocytic leukemia (CLL). In this study, we investigated...
3.
Plesingerova H, Janovska P, Mishra A, Smyckova L, Poppova L, Libra A, et al.
Haematologica . 2017 Nov; 103(2):313-324. PMID: 29122990
Chronic lymphocytic leukemia is a disease with up-regulated expression of the transmembrane tyrosine-protein kinase ROR1, a member of the Wnt/planar cell polarity pathway. In this study, we identified COBLL1 as...
4.
Poppova L, Janovska P, Plevova K, Radova L, Plesingerova H, Borsky M, et al.
Br J Haematol . 2016 Sep; 175(5):851-859. PMID: 27651098
The canonical Wnt pathway, dependent on β-catenin-controlled transcription, is the most explored Wnt pathway, known to drive the malignant transformation of multiple cell types. Several reports have suggested that this...
5.
Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, et al.
Clin Cancer Res . 2015 Aug; 22(2):459-69. PMID: 26240275
Purpose: ROR1, a receptor in the noncanonical Wnt/planar cell polarity (PCP) pathway, is upregulated in malignant B cells of chronic lymphocytic leukemia (CLL) patients. It has been shown that the...