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Lucia Piazza

Explore the profile of Lucia Piazza including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 25
Followers 0
Related Specialties
Chemistry
Biochemistry
Biology
Top 10 Co-Authors
Francesco Balestri
Antonella Del Corso
Marialuisa Menna
Paolo Paoli
Concetta Imperatore
Massimo Genovese
Marcello Casertano
Roberta Moschini
Rossella Mosca
Gemma Sardelli
Published In
Int J Mol Sci
Biology (Basel)
Bioorg Chem
Mar Drugs
Pharmaceutics
Affiliations
Soon will be listed here.
Recent Articles
1.
Glycoconjugate coumarins exploiting metabolism-enhanced fluorescence and preferential uptake: New optical tools for tumor cell staining
Iacopini D, Santi M, Santangelo M, Sardelli G, Piazza L, Mosca R, et al.
Bioorg Chem . 2024 Sep; 153:107836. PMID: 39326338
The possibility to visually discriminate cells based on their metabolism and capability to uptake exogenous molecules is an important topic with exciting fallback on translational and precision medicine. To this...
2.
Is Micronutrient Supplementation Helpful in Supporting the Immune System during Prolonged, High-Intensity Physical Training?
Felice F, Moschini R, Cappiello M, Sardelli G, Mosca R, Piazza L, et al.
Nutrients . 2024 Sep; 16(17). PMID: 39275323
It is well known that during prolonged, high-intensity physical training, athletes experience a state of immunosuppression and that balanced nutrition can help maintain immunity. This review summarizes the effects (amplified...
3.
Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge
Casertano M, Genovese M, Santi A, Pranzini E, Balestri F, Piazza L, et al.
Pharmaceutics . 2023 Feb; 15(2). PMID: 36839851
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by impaired glucose homeostasis and serious long-term complications. First-line therapeutic options for T2DM treatment are monodrug therapies, often replaced by...
4.
Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches
Balestri F, Poli G, Piazza L, Cappiello M, Moschini R, Signore G, et al.
Biology (Basel) . 2022 Sep; 11(9). PMID: 36138801
The inhibition of aldose reductase is considered as a strategy to counteract the onset of both diabetic complications, upon the block of glucose conversion in the polyol pathway, and inflammation,...
5.
Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs
Casertano M, Genovese M, Piazza L, Balestri F, Del Corso A, Vito A, et al.
Pharmaceuticals (Basel) . 2022 Mar; 15(3). PMID: 35337123
Diabetes mellitus (DM) represents a complex and multifactorial disease that causes metabolic disorders with acute and long-term serious complications. The onset of DM, with over 90% of cases of diabetes...
6.
Dual Targeting of PTP1B and Aldose Reductase with Marine Drug Phosphoeleganin: A Promising Strategy for Treatment of Type 2 Diabetes
Genovese M, Imperatore C, Casertano M, Aiello A, Balestri F, Piazza L, et al.
Mar Drugs . 2021 Oct; 19(10). PMID: 34677434
An in-depth study on the inhibitory mechanism on protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AR) enzymes, including analysis of the insulin signalling pathway, of phosphoeleganin, a marine-derived phosphorylated...
7.
Cytosolic 5'-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway
Pesi R, Allegrini S, Garcia-Gil M, Piazza L, Moschini R, Jordheim L, et al.
Int J Mol Sci . 2021 Jul; 22(13). PMID: 34209768
Cytosolic 5'-nucleotidase II (cN-II) is an allosteric catabolic enzyme that hydrolyzes IMP, GMP, and AMP. The enzyme can assume at least two different structures, being the more active conformation stabilized...