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Concetta Imperatore

Explore the profile of Concetta Imperatore including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 332
Followers 0
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Recent Articles
1.
Spacho N, Casertano M, Imperatore C, Papadopoulos C, Menna M, Eleftheriadis N
Chemistry . 2024 Jul; 30(53):e202402279. PMID: 39041705
Human 15-lipoxygenase-1 (15-LOX-1) is a key enzyme that possesses an important role in (neuro)inflammatory diseases. The pocket of the enzyme plays the role of a chiral catalyst, and therefore chirality...
2.
Agognon A, Casertano M, Vito A, Orso S, Cabaro S, Mormone F, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892230
Marine natural products constitute a great source of potential new antidiabetic drugs. The aim of this study was to evaluate the role of phosphoeleganin (PE), a polyketide purified from the...
3.
Casertano M, Esposito E, Bello I, Indolfi C, Putra M, Di Cesare Mannelli L, et al.
Mar Drugs . 2023 Dec; 21(12). PMID: 38132963
Hydrogen sulfide (HS) is a signaling molecule endogenously produced within mammals' cells that plays an important role in inflammation, exerting anti-inflammatory effects. In this view, the research has shown a...
4.
Casertano M, Vito A, Aiello A, Imperatore C, Menna M
Pharmaceutics . 2023 Sep; 15(9). PMID: 37765290
Background: Type 2 diabetes mellitus (T2DM) is an ongoing, risky, and costly health problem that therefore always requires new treatment options. Moreover, although several drugs are available, only 36% of...
5.
Casertano M, Genovese M, Santi A, Pranzini E, Balestri F, Piazza L, et al.
Pharmaceutics . 2023 Feb; 15(2). PMID: 36839851
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by impaired glucose homeostasis and serious long-term complications. First-line therapeutic options for T2DM treatment are monodrug therapies, often replaced by...
6.
Casertano M, Genovese M, Piazza L, Balestri F, Del Corso A, Vito A, et al.
Pharmaceuticals (Basel) . 2022 Mar; 15(3). PMID: 35337123
Diabetes mellitus (DM) represents a complex and multifactorial disease that causes metabolic disorders with acute and long-term serious complications. The onset of DM, with over 90% of cases of diabetes...
7.
Casertano M, Genovese M, Paoli P, Santi A, Aiello A, Menna M, et al.
Mar Drugs . 2022 Jan; 20(1). PMID: 35049920
The chemical investigation of the Mediterranean ascidian has led to the isolation of a new lepadin, named lepadin L, and two known metabolites belonging to the same family, lepadins A...
8.
Genovese M, Imperatore C, Casertano M, Aiello A, Balestri F, Piazza L, et al.
Mar Drugs . 2021 Oct; 19(10). PMID: 34677434
An in-depth study on the inhibitory mechanism on protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AR) enzymes, including analysis of the insulin signalling pathway, of phosphoeleganin, a marine-derived phosphorylated...
9.
Singh M, Zannella C, Folliero V, Di Girolamo R, Bajardi F, Chianese A, et al.
Front Bioeng Biotechnol . 2020 Oct; 8:569967. PMID: 33117781
Interactions of novel bi-dimensional nanomaterials and live matter such as bacteria and viruses represent an extremely hot topic due to the unique properties of the innovative nanomaterials, capable in some...
10.
Imperatore C, Varriale A, Rivieccio E, Pennacchio A, Staiano M, DAuria S, et al.
Int J Mol Sci . 2020 Sep; 21(19). PMID: 32993097
The synthesis of two 5'-end (4-dimethylamino)azobenzene conjugated G-quadruplex forming aptamers, the thrombin binding aptamer (TBA) and the HIV-1 integrase aptamer (T30695), was performed. Their structural behavior was investigated by means...