Lucas Pozzo-Miller
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Explore the profile of Lucas Pozzo-Miller including associated specialties, affiliations and a list of published articles.
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63
Citations
2458
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Recent Articles
1.
Gold W, Percy A, Neul J, Cobb S, Pozzo-Miller L, Issar J, et al.
Nat Rev Dis Primers
. 2024 Nov;
10(1):84.
PMID: 39511247
Rett syndrome (RTT) is a severe, progressive, neurodevelopmental disorder, which affects predominantly females. In most cases, RTT is associated with pathogenic variants in MECP2. MeCP2, the protein product of MECP2,...
2.
Medeiros D, Polepalli L, Li W, Pozzo-Miller L
bioRxiv
. 2024 Aug;
PMID: 39149275
Social memory impairments in knockout (KO) mice result from altered neuronal activity in the monosynaptic projection from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC). The hippocampal network...
3.
Medeiros D, Ayala-Baylon K, Egido-Betancourt H, Miller E, Chapleau C, Robinson H, et al.
Dis Model Mech
. 2024 May;
17(6).
PMID: 38785269
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in MECP2, which encodes methyl-CpG-binding protein 2, a transcriptional regulator of many genes, including brain-derived neurotrophic factor (BDNF). BDNF levels...
4.
Medeiros D, Ayala-Baylon K, Egido-Betancourt H, Miller E, Chapleau C, Robinson H, et al.
bioRxiv
. 2023 Nov;
PMID: 37986936
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in methyl-CpG-binding protein-2 (MECP2), encoding a transcriptional regulator of many genes, including brain-derived neurotrophic factor (Bdnf). BDNF mRNA and protein...
5.
Thomas R, Hernandez A, Benavides D, Li W, Tan C, Umfress A, et al.
J Biol Chem
. 2022 Jul;
298(8):102245.
PMID: 35835216
Cortical glutamate and midbrain dopamine neurotransmission converge to mediate striatum-dependent behaviors, while maladaptations in striatal circuitry contribute to mental disorders. However, the crosstalk between glutamate and dopamine signaling has not...
6.
Hao X, Li Z, Li W, Katz J, Michalek S, Barnum S, et al.
Front Immunol
. 2022 Feb;
13:816640.
PMID: 35178049
Periodontitis is a dysbiotic infectious disease that leads to the destruction of tooth supporting tissues. There is increasing evidence that periodontitis may affect the development and severity of Alzheimer's disease...
7.
Phillips M, Pozzo-Miller L
Bio Protoc
. 2021 Mar;
10(17):e3744.
PMID: 33659404
Determining the neuronal circuitry responsible for specific behaviors is a major focus in the field of neurobiology. Activity-dependent immediate early genes (IEGs), transcribed and translated shortly after neurons discharge action...
8.
Li W, Pozzo-Miller L
J Neurosci Res
. 2019 Nov;
98(11):2130-2147.
PMID: 31758607
The corticostriatal pathway that carries sensory, motor, and limbic information to the striatum plays a critical role in motor control, action selection, and reward. Dysfunction of this pathway is associated...
9.
Li W, Pozzo-Miller L
eNeuro
. 2019 Nov;
6(6).
PMID: 31744842
Excitatory neurons in the primary motor cortex project bilaterally to the striatum. However, whether synaptic structure and function in ipsilateral and contralateral cortico-striatal pathways is identical or different remains largely...
10.
Robinson H, Pozzo-Miller L
Learn Mem
. 2019 Aug;
26(9):343-350.
PMID: 31416907
Gene transcription is a crucial step in the sequence of molecular, synaptic, cellular, and systems mechanisms underlying learning and memory. Here, we review the experimental evidence demonstrating that alterations in...