Lucas Patel
Overview
Explore the profile of Lucas Patel including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
166
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Recent Articles
1.
Salido R, Zhao H, McDonald D, Mannochio-Russo H, Zuffa S, Oles R, et al.
Cell
. 2025 Feb;
PMID: 40020666
Space habitation provides unique challenges in built environments isolated from Earth. We produced a 3D map of the microbes and metabolites throughout the United States Orbital Segment (USOS) of the...
2.
Bhute S, Sanders J, Song S, Lavoie S, Swafford A, Guccione C, et al.
Mol Biol Rep
. 2025 Feb;
52(1):258.
PMID: 39982577
Background: Host DNA depletion is a critical tool for accessing the microbiomes of samples that have a small amount of microbial DNA contained in a high host background. Of critical...
3.
Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore G, et al.
Nat Commun
. 2025 Jan;
16(1):825.
PMID: 39827261
As next-generation sequencing technologies produce deeper genome coverages at lower costs, there is a critical need for reliable computational host DNA removal in metagenomic data. We find that insufficient host...
4.
Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore G, et al.
Res Sq
. 2024 Nov;
PMID: 39502785
As next-generation sequencing technologies produce deeper genome coverages at lower costs, there is a critical need for reliable computational host DNA removal in metagenomic data. We find that insufficient host...
5.
Ornish D, Madison C, Kivipelto M, Kemp C, McCulloch C, Galasko D, et al.
Alzheimers Res Ther
. 2024 Jun;
16(1):122.
PMID: 38849944
Background: Evidence links lifestyle factors with Alzheimer's disease (AD). We report the first randomized, controlled clinical trial to determine if intensive lifestyle changes may beneficially affect the progression of mild...
6.
Liu E, Yang J, Patel L, Arora J, Gooding A, Ellis R, et al.
J Neurol
. 2023 Jul;
270(10):4661-4672.
PMID: 37493802
Background: Persistent neuropsychiatric symptoms following acute COVID-19 infection are frequently reported. These include anxiety, depression, difficulty concentrating, fatigue, and insomnia. The longitudinal evolution of this neuropsychiatric burden is poorly understood...
7.
Lau R, Ye Q, Birkholz E, Berg K, Patel L, Mathews I, et al.
Mol Cell
. 2020 Jan;
77(4):723-733.e6.
PMID: 31932164
Bacteria possess an array of defenses against foreign invaders, including a broadly distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti-phage signaling system). In CBASS systems, a cGAS/DncV-like nucleotidyltransferase synthesizes...
8.
Patel L, Kang R, Rosenberg S, Qiu Y, Raviram R, Chee S, et al.
Nat Struct Mol Biol
. 2019 Feb;
26(3):164-174.
PMID: 30778236
In meiotic prophase, chromosomes are organized into compacted loop arrays to promote homolog pairing and recombination. Here, we probe the architecture of the mouse spermatocyte genome in early and late...