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Luca Pinton

Explore the profile of Luca Pinton including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 275
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Recent Articles
1.
Pinton L, Khedr M, Lionello V, Sarcar S, Maffioletti S, Dastidar S, et al.
Nat Protoc . 2023 Feb; 18(4):1337-1376. PMID: 36792780
Skeletal muscle is a complex tissue composed of multinucleated myofibers responsible for force generation that are supported by multiple cell types. Many severe and lethal disorders affect skeletal muscle; therefore,...
2.
Vignier N, Chatzifrangkeskou M, Pinton L, Wioland H, Marais T, Lemaitre M, et al.
Cell Rep . 2021 Aug; 36(8):109601. PMID: 34433058
Cofilins are important for the regulation of the actin cytoskeleton, sarcomere organization, and force production. The role of cofilin-1, the non-muscle-specific isoform, in muscle function remains unclear. Mutations in LMNA...
3.
Borroto-Escuela D, Narvaez M, Romero-Fernandez W, Pinton L, Wydra K, Filip M, et al.
Mol Neurobiol . 2019 Apr; 56(10):7045-7055. PMID: 30972626
The current study was performed to establish the actions of nanomolar concentrations of cocaine, not blocking the dopamine transporter, on dopamine D2 receptor (DR)-sigma 1 receptor (δ1R) heteroreceptor complexes and...
4.
Steele-Stallard H, Pinton L, Sarcar S, Ozdemir T, Maffioletti S, Zammit P, et al.
Front Physiol . 2018 Nov; 9:1332. PMID: 30405424
Laminopathies are a clinically heterogeneous group of disorders caused by mutations in . The main proteins encoded by are Lamin A and C, which together with Lamin B1 and B2,...
5.
Maffioletti S, Sarcar S, Henderson A, Mannhardt I, Pinton L, Moyle L, et al.
Cell Rep . 2018 Apr; 23(3):899-908. PMID: 29669293
Generating human skeletal muscle models is instrumental for investigating muscle pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial skeletal muscle tissue from human pluripotent stem cells,...
6.
Feltmann K, Borroto-Escuela D, Ruegg J, Pinton L, Sergio T, Narvaez M, et al.
Alcohol Clin Exp Res . 2017 Dec; 42(2):338-351. PMID: 29205397
Background: Reduced dopamine D2 receptor (D2R) ligand binding has repeatedly been demonstrated in the striatum of humans with alcohol use disorder (AUD). The attenuated D2R binding has been suggested to...
7.
Borroto-Escuela D, Narvaez M, Wydra K, Pintsuk J, Pinton L, Jimenez-Beristain A, et al.
Pharmacol Biochem Behav . 2017 Mar; 155:24-31. PMID: 28300546
Adenosine 2A receptor (A2AR) agonists were indicated to reduce cocaine reward and cocaine seeking mainly through activation of antagonistic allosteric A2AR-dopamine D2R (D2R) interactions in A2AR-D2R heteroreceptor complexes. Furthermore, it...