Francesco Saverio Tedesco
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Explore the profile of Francesco Saverio Tedesco including associated specialties, affiliations and a list of published articles.
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48
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1755
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Recent Articles
1.
Valdebenito G, Chacko A, Chung C, Sheshadri P, Chi H, OCallaghan B, et al.
Stem Cell Reports
. 2025 Mar;
:102448.
PMID: 40086445
Mutations in mitochondrial DNA cause severe multisystem disease frequently associated with muscle weakness. The m.3243A>G mutation is the major cause of mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes (MELAS). Experimental...
2.
Jiang Y, Devito L, Muntoni F, Healy L, Tedesco F
Stem Cell Res
. 2025 Jan;
83:103648.
PMID: 39764974
Ullrich congenital muscular dystrophy (UCMD) represents the most severe subtype of collagen VI-related dystrophies (COL6-RDs), a spectrum of rare extracellular matrix disorders affecting skeletal muscle and connective tissue. Here, we...
3.
Mishra S, Welch N, Singh S, Singh K, Bellar A, Kumar A, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(31):e2314760121.
PMID: 39052834
Transceptors, solute transporters that facilitate intracellular entry of molecules and also initiate intracellular signaling events, have been primarily studied in lower-order species. Ammonia, a cytotoxic endogenous metabolite, is converted to...
4.
Hagemann C, Bailey M, Carraro E, Stankevich K, Lionello V, Khokhar N, et al.
PLoS Biol
. 2024 Mar;
22(3):e3002503.
PMID: 38478490
Cell culture devices, such as microwells and microfluidic chips, are designed to increase the complexity of cell-based models while retaining control over culture conditions and have become indispensable platforms for...
5.
Devito L, Lionello V, Muntoni F, Tedesco F, Healy L
Stem Cell Res
. 2023 Mar;
69:103079.
PMID: 36989620
Centronuclear myopathies (CNMs) are a group of inherited rare muscle disorders characterised by the abnormal position of the nucleus in the center of the muscle fiber. One of CNM is...
6.
Pinton L, Khedr M, Lionello V, Sarcar S, Maffioletti S, Dastidar S, et al.
Nat Protoc
. 2023 Feb;
18(4):1337-1376.
PMID: 36792780
Skeletal muscle is a complex tissue composed of multinucleated myofibers responsible for force generation that are supported by multiple cell types. Many severe and lethal disorders affect skeletal muscle; therefore,...
7.
Cossu G, Tonlorenzi R, Brunelli S, Sampaolesi M, Messina G, Azzoni E, et al.
Front Genet
. 2023 Jan;
13:1056114.
PMID: 36685855
In 2002 we published an article describing a population of vessel-associated progenitors that we termed mesoangioblasts (MABs). During the past decade evidence had accumulated that during muscle development and regeneration...
8.
Choi S, Ferrari G, Moyle L, Mackinlay K, Naouar N, Jalal S, et al.
EMBO Mol Med
. 2022 Sep;
14(10):e14526.
PMID: 36161772
Muscle satellite stem cells (MuSCs) are responsible for skeletal muscle growth and regeneration. Despite their differentiation potential, human MuSCs have limited in vitro expansion and in vivo migration capacity, limiting...
9.
Jiang Y, Torun T, Maffioletti S, Serio A, Tedesco F
Exp Cell Res
. 2022 Apr;
416(2):113133.
PMID: 35427601
Engineering models of human skeletal muscle tissue provides unique translational opportunities to investigate and develop therapeutic strategies for acute muscle injuries, and to establish personalised and precision medicine platforms for...
10.
Chesshyre M, Ridout D, Hashimoto Y, Ookubo Y, Torelli S, Maresh K, et al.
J Cachexia Sarcopenia Muscle
. 2022 Jan;
13(2):1360-1372.
PMID: 35083887
Background: Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to dystrophin loss. Full-length Dp427 is the primary dystrophin isoform expressed in muscle and is also expressed in the...