Luay Almassalha
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Explore the profile of Luay Almassalha including associated specialties, affiliations and a list of published articles.
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15
Citations
94
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Recent Articles
1.
Almassalha L, MacQuarrie K
Med
. 2025 Mar;
6(3):100610.
PMID: 40088882
Physician-scientists are a small proportion of the physician workforce. As early-career near-peer physician-scientists, we find value in the intersection of our expertise. This "percolation" overcomes both systemic and individual barriers....
2.
Bunner S, Prince K, Pujadas Liwag E, Eskndir N, Srikrishna K, Amonu McCarthy A, et al.
J Cell Sci
. 2024 Nov;
138(3).
PMID: 39501901
Nuclear blebs are herniations of the nucleus that occur in diseased nuclei and cause nuclear rupture leading to cellular dysfunction. Chromatin and lamins are two of the major structural components...
3.
Acosta N, Gong R, Su Y, Frederick J, Medina K, Li W, et al.
bioRxiv
. 2024 Sep;
PMID: 39314277
Super-resolution microscopy has revolutionized our ability to visualize structures below the diffraction limit of conventional optical microscopy and is particularly useful for investigating complex biological targets like chromatin. Chromatin exhibits...
4.
Kant A, Guo Z, Vinayak V, Neguembor M, Li W, Agrawal V, et al.
Nat Commun
. 2024 May;
15(1):4338.
PMID: 38773126
In interphase nuclei, chromatin forms dense domains of characteristic sizes, but the influence of transcription and histone modifications on domain size is not understood. We present a theoretical model exploring...
5.
Bunner S, Prince K, Srikrishna K, Pujadas E, Amonu McCarthy A, Kuklinski A, et al.
bioRxiv
. 2024 Feb;
PMID: 38370828
Nuclear blebs are herniations of the nucleus that occur in diseased nuclei that cause nuclear rupture leading to cellular dysfunction. Chromatin and lamins are two of the major structural components...
6.
Ibarra J, Hershenhouse T, Almassalha L, Walterhouse D, Backman V, MacQuarrie K
Front Cell Dev Biol
. 2023 Nov;
11:1293891.
PMID: 38020905
Myogenesis, the progression of proliferating skeletal myoblasts to terminally differentiated myotubes, regulates thousands of target genes. Uninterrupted linear arrays of such genes are differentially associated with specific chromosomes, suggesting chromosome...
7.
Carignano M, Kroger M, Almassalha L, Agrawal V, Li W, Pujadas E, et al.
Res Sq
. 2023 Oct;
PMID: 37886531
We propose the Self Returning Excluded Volume (SR-EV) model for the structure of chromatin based on stochastic rules and physical interactions that is able to capture the observed behavior across...
8.
Spicer G, Almassalha L, Martinez I, Ellis R, Chandler J, Gladstein S, et al.
Nanoscale
. 2023 Jul;
15(28):12124.
PMID: 37435809
Correction for 'Label free localization of nanoparticles in live cancer cells using spectroscopic microscopy' by Graham L. C. Spicer , , 2018, , 19125-19130, https://doi.org/10.1039/C8NR07481J.
9.
Pujadas E, Wei X, Acosta N, Carter L, Yang J, Almassalha L, et al.
bioRxiv
. 2023 Jul;
PMID: 37425796
Background: B-type lamins are critical nuclear envelope proteins that interact with the 3D genomic architecture. However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as...
10.
Ibarra J, Hershenhouse T, Almassalha L, MacQuarrie K
bioRxiv
. 2023 May;
PMID: 37214969
Myogenesis, the progression of proliferating skeletal myoblasts to terminally differentiated myotubes, regulates thousands of target genes. Uninterrupted linear arrays of such genes are differentially associated with specific chromosomes, suggesting chromosome...