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Loukia Katsouri

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Articles 18
Citations 491
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Recent Articles
1.
Watamura N, Foiani M, Bez S, Bourdenx M, Santambrogio A, Frodsham C, et al.
Nat Neurosci . 2024 Dec; 28(2):293-307. PMID: 39719507
Tau pathology is a hallmark of several neurodegenerative diseases, including frontotemporal dementia and Alzheimer's disease. However, the sequence of events and the form of tau that confers toxicity are still...
2.
Muza P, Perez M, Noy S, Kurosawa M, Katsouri L, Tybulewicz V, et al.
BMC Res Notes . 2023 Sep; 16(1):246. PMID: 37777793
Traditional histological analysis is conducted on thin tissue sections, limiting the data capture from large tissue volumes to 2D profiles, and requiring stereological methods for 3D assessment. Recent advances in...
3.
Mirzaei N, Mota B, Birch A, Davis N, Romero-Molina C, Katsouri L, et al.
Br J Pharmacol . 2020 Nov; 178(3):654-671. PMID: 33140839
Background And Purpose: Activation of type 2 imidazoline receptors has been shown to exhibit neuroprotective properties including anti-apoptotic and anti-inflammatory effects, suggesting a potential therapeutic value in Alzheimer's disease (AD)....
4.
Katsouri L, Birch A, Renziehausen A, Zach C, Aman Y, Steeds H, et al.
Glia . 2019 Dec; 68(5):1017-1030. PMID: 31799735
The role of astrocytes in the progression of Alzheimer's disease (AD) remains poorly understood. We assessed the consequences of ablating astrocytic proliferation in 9 months old double transgenic APP23/GFAP-TK mice....
5.
Irvine E, Katsouri L, Plattner F, Al-Qassab H, Al-Nackkash R, Bates G, et al.
Sci Rep . 2019 Nov; 9(1):16133. PMID: 31695068
Huntington's disease (HD) is a fatal inherited autosomal dominant neurodegenerative disorder caused by an expansion in the number of CAG trinucleotide repeats in the huntingtin gene. The disease is characterized...
6.
Smith M, Katsouri L, Virtue S, Choudhury A, Vidal-Puig A, Ashford M, et al.
Cell Rep . 2018 Oct; 25(2):278-287.e4. PMID: 30304668
Leptin acts on hypothalamic pro-opiomelanocortin (POMC) neurons to regulate glucose homeostasis, but the precise mechanisms remain unclear. Here, we demonstrate that leptin-induced depolarization of POMC neurons is associated with the...
7.
Viskaitis P, Irvine E, Smith M, Choudhury A, Alvarez-Curto E, Glegola J, et al.
Cell Rep . 2017 Dec; 21(12):3559-3572. PMID: 29262334
Feeding requires the integration of homeostatic drives with emotional states relevant to food procurement in potentially hostile environments. The ventromedial hypothalamus (VMH) regulates feeding and anxiety, but how these are...
8.
Katsouri L, Lim Y, Blondrath K, Eleftheriadou I, Lombardero L, Birch A, et al.
Proc Natl Acad Sci U S A . 2016 Oct; 113(43):12292-12297. PMID: 27791018
Current therapies for Alzheimer's disease (AD) are symptomatic and do not target the underlying Aβ pathology and other important hallmarks including neuronal loss. PPARγ-coactivator-1α (PGC-1α) is a cofactor for transcription...
9.
Blondrath K, Steel J, Katsouri L, Ries M, Parker M, Christian M, et al.
Neurobiol Aging . 2016 Sep; 47:180-191. PMID: 27614112
The receptor interacting protein-140 (RIP140) is a cofactor for several nuclear receptors and has been involved in the regulation of metabolic and inflammatory genes. We hypothesize that RIP140 may also...
10.
Smith M, Katsouri L, Irvine E, Hankir M, Pedroni S, Voshol P, et al.
Cell Rep . 2015 Apr; 11(3):335-43. PMID: 25865886
Hypothalamic ribosomal S6K1 has been suggested as a point of convergence for hormonal and nutrient signals in the regulation of feeding behavior, bodyweight, and glucose metabolism. However, the long-term effects...