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Louise Cadzow

Explore the profile of Louise Cadzow including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 16
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Recent Articles
1.
Dodson A, Shenker S, Sullivan P, Nayak S, Middleton C, McGuire M, et al.
Cancer Res Commun . 2024 Nov; 4(12):3084-3098. PMID: 39485057
HRD is common in cancer and can be exploited therapeutically, as it sensitizes cells to DNA-damaging agents. Here, we scored more than 1,300 cancer cell lines for HRD using two...
2.
Cadzow L, Brenneman J, Tobin E, Sullivan P, Nayak S, Ali J, et al.
Cancer Res . 2024 Oct; 84(20):3419-3434. PMID: 39402989
Defects in DNA repair pathways play a pivotal role in tumor evolution and resistance to therapy. At the same time, they create vulnerabilities that render tumors dependent on the remaining...
3.
Schlabach M, Lin S, Collester Z, Wrocklage C, Shenker S, Calnan C, et al.
J Clin Invest . 2023 Dec; 133(24). PMID: 38099496
Cell therapies such as tumor-infiltrating lymphocyte (TIL) therapy have shown promise in the treatment of patients with refractory solid tumors, with improvement in response rates and durability of responses nevertheless...
4.
Georgiev P, Muise E, Linn D, Hinton M, Wang Y, Cai M, et al.
Mol Cancer Ther . 2021 Dec; 21(3):427-439. PMID: 34965960
Targeting the programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway with immunotherapy has revolutionized the treatment of many cancers. Somatic tumor mutational burden (TMB) and T-cell-inflamed gene expression profile (GEP)...