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Louisa P E Dunlevy

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Recent Articles
1.
Sudiwala S, Palmer A, Massa V, Burns A, Dunlevy L, de Castro S, et al.
Dis Model Mech . 2019 Oct; 12(11). PMID: 31636139
Neural tube defects (NTDs), including spina bifida and anencephaly, are among the most common birth defects worldwide, but their underlying genetic and cellular causes are not well understood. Some NTDs...
2.
Dunlevy L, Chitty L, Burren K, Doudney K, Stojilkovic-Mikic T, Stanier P, et al.
Brain . 2007 Apr; 130(Pt 4):1043-9. PMID: 17438019
Folic acid supplementation can prevent many cases of neural tube defects (NTDs), whereas suboptimal maternal folate status is a risk factor, suggesting that folate metabolism is a key determinant of...
3.
Dunlevy L, Burren K, Mills K, Chitty L, Copp A, Greene N
Birth Defects Res A Clin Mol Teratol . 2006 Aug; 76(7):544-52. PMID: 16933307
Background: Closure of the cranial neural tube during embryogenesis is a crucial process in development of the brain. Failure of this event results in the severe neural tube defect (NTD)...
4.
Dunlevy L, Burren K, Chitty L, Copp A, Greene N
FEBS Lett . 2006 May; 580(11):2803-7. PMID: 16674949
Suppression of one-carbon metabolism or insufficient methionine intake are suggested to increase risk of neural tube defects (NTD). Here, exogenous methionine unexpectedly caused frequent NTD in cultured mouse embryos. NTD...
5.
Cogram P, Hynes A, Dunlevy L, Greene N, Copp A
Hum Mol Genet . 2003 Nov; 13(1):7-14. PMID: 14613966
A proportion of neural tube defects (NTDs) can be prevented by maternal folic acid supplementation, although some cases are unresponsive. The curly tail mutant mouse provides a model of folate-resistant...