Lorrie A Kirshenbaum
Overview
Explore the profile of Lorrie A Kirshenbaum including associated specialties, affiliations and a list of published articles.
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Articles
118
Citations
8905
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Recent Articles
21.
Rabinovich-Nikitin I, Cogan R, Kirshenbaum L
Circ Res
. 2021 Dec;
129(12):1122-1124.
PMID: 34855463
No abstract available.
22.
Marian A, Asatryan B, Bolli R, Cheedipudi S, Dhalla N, Finkel T, et al.
J Cardiovasc Aging
. 2021 Jul;
1.
PMID: 34327514
No abstract available.
23.
Rabinovich-Nikitin I, Rasouli M, Reitz C, Posen I, Margulets V, Dhingra R, et al.
Autophagy
. 2021 Jun;
17(11):3794-3812.
PMID: 34085589
Cardiac function is highly reliant on mitochondrial oxidative metabolism and quality control. The circadian gene is critically linked to vital physiological processes including mitochondrial fission, fusion and bioenergetics; however, little...
24.
Rabinovich-Nikitin I, Kirshenbaum L
J Clin Invest
. 2021 Mar;
131(5).
PMID: 33645545
Lysosomal storage disorders (LSD) are a group of inherited metabolic diseases characterized by lysosomal enzyme deficiency. The cardiac phenotype includes cardiomyopathy with eventual heart failure. Lysosome-mediated degradation processes, such as...
25.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
26.
Aghanoori M, Margulets V, Smith D, Kirshenbaum L, Gitler D, Fernyhough P
Mol Metab
. 2021 Feb;
49:101191.
PMID: 33592336
Objective: The distal dying-back of the longest nerve fibres is a hallmark of diabetic neuropathy, and impaired provision of energy in the form of adenosine triphosphate (ATP) may contribute to...
27.
Stamenkovic A, OHara K, Nelson D, Maddaford T, Edel A, Maddaford G, et al.
Am J Physiol Heart Circ Physiol
. 2021 Jan;
320(3):H1170-H1184.
PMID: 33513080
Myocardial ischemia-reperfusion (I/R) injury increases the generation of oxidized phosphatidylcholines (OxPCs), which results in cell death. However, the mechanism by which OxPCs mediate cell death and cardiac dysfunction is largely...
28.
Aziz I, McMahon A, Friedman D, Rabinovich-Nikitin I, Kirshenbaum L, Martino T
Curr Opin Pharmacol
. 2020 Dec;
57:60-70.
PMID: 33340915
Circadian rhythms follow a 24 h day and night cycle, regulate vital physiological processes, and are especially relevant to cardiovascular growth, renewal, repair, and remodeling. A recent flurry of clinical...
29.
Sareen N, Abu-El-Rub E, Ammar H, Yan W, Sequiera G, ShamsEldeen A, et al.
FASEB J
. 2020 Sep;
34(11):15236-15251.
PMID: 32959405
Allogeneic mesenchymal stem cells (MSCs) from young and healthy donors are reported to hold the potential to treat several immunological and degenerative disorders. However, recent data from animal studies and...
30.
Amgalan D, Garner T, Pekson R, Jia X, Yanamandala M, Paulino V, et al.
Nat Cancer
. 2020 Aug;
1(3):315-328.
PMID: 32776015
Doxorubicin remains an essential component of many cancer regimens, but its use is limited by lethal cardiomyopathy, which has been difficult to target, owing to pleiotropic mechanisms leading to apoptotic...