Lorrie A Kirshenbaum
Overview
Explore the profile of Lorrie A Kirshenbaum including associated specialties, affiliations and a list of published articles.
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118
Citations
8905
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Recent Articles
11.
Yakobov S, Dhingra R, Margulets V, Dhingra A, Crandall M, Kirshenbaum L
Mol Cell Biochem
. 2023 Jan;
478(9):2029-2040.
PMID: 36607523
Anthracyclines such as doxorubicin (Dox) are widely used to treat a variety of adult and childhood cancers, however, a major limitation to many of these compounds is their propensity for...
12.
Rabinovich-Nikitin I, Crandall M, Kirshenbaum L
Can J Physiol Pharmacol
. 2022 Nov;
101(1):1-7.
PMID: 36318826
Cardiovascular disease is the leading cause of morbidity and mortality worldwide. However, sex differences can impact differently the etiology and outcome of cardiovascular disease when comparing men and women. Women...
13.
Rabinovich-Nikitin I, Kirshenbaum L
Trends Cardiovasc Med
. 2022 Sep;
34(1):1-7.
PMID: 36150629
Circadian mechanisms have been associated with the pathogenesis of a variety of cardiovascular diseases, including myocardial ischemia-reperfusion injury (I-R). Myocardial ischemia resulting from impaired oxygen delivery to cardiac muscle sets...
14.
Dhingra R, Rabinovich-Nikitin I, Rothman S, Guberman M, Gang H, Margulets V, et al.
Circulation
. 2022 Aug;
146(12):934-954.
PMID: 35983756
Background: Cytokines such as tumor necrosis factor-α (TNFα) have been implicated in cardiac dysfunction and toxicity associated with doxorubicin (DOX). Although TNFα can elicit different cellular responses, including survival or...
15.
Rabinovich-Nikitin I, Blant A, Dhingra R, Kirshenbaum L, Czubryt M
Cells
. 2022 Jul;
11(14).
PMID: 35883637
Hypoxia exerts broad effects on cardiomyocyte function and viability, ranging from altered metabolism and mitochondrial physiology to apoptotic or necrotic cell death. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator...
16.
Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner T, Rabinovich-Nikitin I, et al.
Nat Commun
. 2022 Jul;
13(1):3775.
PMID: 35798717
Mitofusins reside on the outer mitochondrial membrane and regulate mitochondrial fusion, a physiological process that impacts diverse cellular processes. Mitofusins are activated by conformational changes and subsequently oligomerize to enable...
17.
Dhingra R, Kirshenbaum L
Cardiovasc Res
. 2022 Jun;
118(12):2561-2563.
PMID: 35727951
No abstract available.
18.
Rabinovich-Nikitin I, Kirshenbaum L
Circulation
. 2022 Feb;
145(6):465-468.
PMID: 35130053
No abstract available.
19.
Rabinovich-Nikitin I, Kirshenbaum L
Trends Cardiovasc Med
. 2022 Jan;
33(4):213-214.
PMID: 35092849
No abstract available.
20.
Rabinovich-Nikitin I, Love M, Kirshenbaum L
Biochim Biophys Acta Mol Basis Dis
. 2022 Jan;
1868(4):166354.
PMID: 35065229
Autophagy is a vital cellular mechanism that controls the removal of damaged or dysfunctional cellular components. Autophagy allows the degradation and recycling of damaged proteins and organelles into their basic...