Lorena Rosas
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Explore the profile of Lorena Rosas including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
25
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Recent Articles
1.
Fredriksen T, Holbrook J, Rosas L, Angeles-Lopez Q, Mora A, Rojas M, et al.
Anal Chem
. 2025 Mar;
PMID: 40088151
The lipidome, encompassing the comprehensive lipid fingerprint of a biological system, includes thousands of unique isomeric and isobaric lipid species. Mass spectrometry (MS) is an effective technique for characterizing the...
2.
Reader B, Rosas L, Knopf B, Liu Y, Alzate-Correa D, Bhat A, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Dec;
80(2).
PMID: 39704343
As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of...
3.
Nguyen N, Rosas L, Khaliullin T, Jiang P, Hasanaj E, Ovando-Ricardez J, et al.
Genome Biol
. 2024 Nov;
25(1):288.
PMID: 39516853
The low resolution of spatial transcriptomics data necessitates additional information for optimal use. We developed scDOT, which combines spatial transcriptomics and single cell RNA sequencing to improve the ability to...
4.
Kim J, Buffenstein R, Bronikowski A, Pilar Vanegas N, Rosas L, Agudelo-Garcia P, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Nov;
79(11).
PMID: 39498863
The Midwest Aging Consortium (MAC) has emerged as a critical collaborative initiative aimed at advancing our understanding of aging and developing strategies to combat the rising prevalence of age-related diseases....
5.
Sekera E, Rosas L, Holbrook J, Angeles-Lopez Q, Khaliullin T, Rojas M, et al.
J Am Soc Mass Spectrom
. 2024 Oct;
35(12):2815-2823.
PMID: 39476364
In this study, we evaluate lipids and select proteins in human lung fibroblasts (hLFs) to interrogate changes occurring due to aging and senescence. To study single cell populations, a comparison...
6.
Chen H, Lee Y, Ovando-Ricardez J, Rosas L, Rojas M, Mora A, et al.
Cell Rep Methods
. 2024 Sep;
4(10):100864.
PMID: 39326411
Many popular spatial transcriptomics techniques lack single-cell resolution. Instead, these methods measure the collective gene expression for each location from a mixture of cells, potentially containing multiple cell types. Here,...
7.
Johnson B, Farkas D, El-Mergawy R, Adair J, Elhance A, Eltobgy M, et al.
Nat Commun
. 2024 Jul;
15(1):6172.
PMID: 39039092
The severity of bacterial pneumonia can be worsened by impaired innate immunity resulting in ineffective pathogen clearance. We describe a mitochondrial protein, aspartyl-tRNA synthetase (DARS2), which is released in circulation...
8.
El-Mergawy R, Chafin L, Ovando-Ricardez J, Rosas L, Tsai M, Rojas M, et al.
J Biol Chem
. 2024 May;
300(6):107359.
PMID: 38735474
FOXK2 is a crucial transcription factor implicated in a wide array of biological activities and yet understanding of its molecular regulation at the level of protein turnover is limited. Here,...
9.
Sekera E, Rosas L, Holbrook J, Angeles-Lopez Q, Khaliullin T, Rojas M, et al.
bioRxiv
. 2024 Apr;
PMID: 38559151
In this study, we evaluate lipids and select proteins in human lung fibroblasts (hLFs) to interrogate changes occurring due to aging and senescence. To study single cell populations, a comparison...
10.
Chen H, Lee Y, Ovando J, Rosas L, Rojas M, Mora A, et al.
bioRxiv
. 2024 Jan;
PMID: 38187629
Many popular spatial transcriptomics techniques lack single-cell resolution. Instead, these methods measure the collective gene expression for each location from a mixture of cells, potentially containing multiple cell types. Here,...