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Lorena Quirico

Explore the profile of Lorena Quirico including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 166
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Recent Articles
1.
Orso F, Virga F, Dettori D, Dalmasso A, Paradzik M, Savino A, et al.
J Exp Clin Cancer Res . 2023 Jan; 42(1):20. PMID: 36639824
Background: Tumor progression is based on a close interaction between cancer cells and Tumor MicroEnvironment (TME). Here, we focus on the role that Cancer Associated Fibroblasts (CAFs), Mesenchymal Stem Cells...
2.
Quirico L, Orso F
Cancer Drug Resist . 2022 May; 3(2):117-139. PMID: 35582611
In the last decades, progresses in medical oncology have ameliorated the treatment of patients and their outcome. However, further improvements are still necessary, in particular for certain types of tumors...
3.
Quirico L, Orso F, Cucinelli S, Paradzik M, Natalini D, Centonze G, et al.
Cell Mol Life Sci . 2022 Mar; 79(4):216. PMID: 35348905
MicroRNAs (miRNAs) are small, non-coding RNAs about 22 nucleotides in length that regulate the expression of target genes post-transcriptionally, and are highly involved in cancer progression. They are able to...
4.
Coppo R, Orso F, Virga F, Dalmasso A, Baruffaldi D, Nie L, et al.
Cancer Lett . 2021 Apr; 510:13-23. PMID: 33862151
An interactive crosstalk between tumor and stroma cells is essential for metastatic melanoma progression. We evidenced that ESDN/DCBLD2/CLCP1 plays a crucial role in endothelial cells during the spread of melanoma....
5.
Virga F, Quirico L, Cucinelli S, Mazzone M, Taverna D, Orso F
Cancers (Basel) . 2021 Jan; 13(1). PMID: 33401522
The metabolism of cancer cells is generally very different from what is found in normal counterparts. However, in a tumor mass, the continuous crosstalk and competition for nutrients and oxygen...
6.
Quirico L, Orso F, Esposito C, Bertone S, Coppo R, Conti L, et al.
Int J Biol Sci . 2020 Mar; 16(7):1238-1251. PMID: 32174798
microRNAs (miRNAs) are small non-coding RNAs acting as negative regulators of gene expression and involved in tumor progression. We recently showed that inhibition of the pro-metastatic miR-214 and simultaneous overexpression...
7.
Orso F, Quirico L, Dettori D, Coppo R, Virga F, Ferreira L, et al.
Semin Cancer Biol . 2019 Aug; 60:214-224. PMID: 31386907
Cancer is a multistep disease based on crucial interactions between tumor cells and the microenvironment (extracellular matrix and stroma/immune cells). In fact, during dissemination, tumor cells have to escape from...
8.
Orso F, Quirico L, Virga F, Penna E, Dettori D, Cimino D, et al.
Cancer Res . 2016 Jun; 76(17):5151-62. PMID: 27328731
miR-214 and miR-148b have been proposed to antagonize the effects of each other in enabling or blocking metastasis, respectively. In this study, we provide evidence deepening their role and interrelationship...