Lutz Ackermann
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Explore the profile of Lutz Ackermann including associated specialties, affiliations and a list of published articles.
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369
Citations
4917
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Recent Articles
1.
Zhang Z, Golling S, Cattani S, Chen X, Ackermann L
J Am Chem Soc
. 2025 Feb;
147(8):6897-6904.
PMID: 39957411
The synthesis of alkylated indoles, which are key intermediates for various drugs and bioactive molecules, is of great importance. However, most reports on the synthesis of functionalized indoles use toxic...
2.
Gou X, Oliveira J, Chen S, Homolle S, Trienes S, von Munchow T, et al.
Chem Sci
. 2024 Dec;
16(2):824-833.
PMID: 39650220
The position-selective C-H bond activation of arenes has long been a challenging topic. Herein, we report an expedient ruthenium-electrocatalyzed site-selective -C-H phosphorylation of arenes driven by electrochemical hydrogen evolution reaction...
3.
Trienes S, Golling S, Gieuw M, Di Matteo M, Ackermann L
Chem Sci
. 2024 Oct;
PMID: 39479157
Hydroarylation reactions have emerged as a valuable tool for the direct functionalization of C-H bonds with ideal atom economy. However, common catalytic variants for these transformations largely require harsh reaction...
4.
Kushwaha P, Saxena A, von Munchow T, Dana S, Saha B, Ackermann L
Chem Commun (Camb)
. 2024 Oct;
60(85):12333-12364.
PMID: 39370984
Alkyne annulation represents a versatile and powerful strategy for the assembly of structurally complex compounds. Recent advances successfully enabled electrocatalytic alkyne annulations, significantly expanding the potential applications of this promising...
5.
Chen W, Xu J, Rao W, Shen S, Yang Z, Ackermann L, et al.
Org Lett
. 2024 Sep;
PMID: 39291854
Herein, we reported a copper(0)-catalyzed reductive coupling of disulfurating reagents and (hetero)aryl/alkyl halides. Copper(0) can be directly inserted into tetrasulfide and then undergoes reductive coupling with (hetero)aryl Iodides to construct...
6.
Lan H, Liu Y, Ackermann L, Wang L, Wang D
Org Lett
. 2024 Sep;
26(38):7993-7998.
PMID: 39264308
An efficient approach for the remote C-H alkylation of arenes, employing a variety of N-directing groups is described. This method facilitates the straightforward synthesis of valuable phenylethylamine derivatives by exclusively...
7.
Hourtoule M, Trienes S, Ackermann L
Angew Chem Int Ed Engl
. 2024 Sep;
63(48):e202412689.
PMID: 39254508
Plastics are omnipresent in our everyday life, and accumulation of post-consumer plastic waste in our environment represents a major societal challenge. Hence, methods for plastic waste recycling are in high...
8.
Xu Y, Lin Y, Homolle S, Oliveira J, Ackermann L
J Am Chem Soc
. 2024 Aug;
146(34):24105-24113.
PMID: 39143928
The quest for sustainable strategies in molecular synthesis has spurred the emergence of photocatalysis as a particularly powerful technique. In recent years, the application of photocatalysis in this context has...
9.
Wu J, Purushothaman R, Kallert F, Homolle S, Ackermann L
ACS Catal
. 2024 Aug;
14(15):11532-11544.
PMID: 39114086
Glycosyl donor activation emerged as an enabling technology for anomeric functionalization, but aimed primarily at -glycosylation. In contrast, we herein disclose mechanistically distinct electrochemical glycosyl bromide donor activations via halogen-atom...
10.
Cheng Y, Xu J, Lin Z, Li Y, Ackermann L
Chemistry
. 2024 Aug;
30(59):e202402333.
PMID: 39096120
Cross-dehydrogenative couplings (CDC) present an efficient strategy for the assembly of biorelevant heterocycles, but are thus far largely limited to toxic transition metals and rather harsh reaction conditions. In sharp...