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Lorena Betancor

Explore the profile of Lorena Betancor including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 312
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Recent Articles
1.
Torres-Herrero B, Armenia I, Ortiz C, de la Fuente J, Betancor L, Grazu V
J Control Release . 2024 Jun; 372:619-647. PMID: 38909702
In recent years, enzyme therapy strategies have rapidly evolved to catalyze essential biochemical reactions with therapeutic potential. These approaches hold particular promise in addressing rare genetic disorders, cancer treatment, neurodegenerative...
2.
Santoyo-Garcia J, Valdivia-Cabrera M, Ochoa-Villarreal M, Casasola-Zamora S, Ripoll M, Escrich A, et al.
Bioresour Bioprocess . 2024 Apr; 10(1):68. PMID: 38647629
In this study, several approaches were tested to optimise the production and recovery of the widely used anticancer drug Taxol (paclitaxel) from culturable vascular stem cells (VSCs) of Taxus baccata,...
3.
Torres-Herrero B, Armenia I, Alleva M, Asin L, Correa S, Ortiz C, et al.
ACS Nano . 2023 Jun; 17(13):12358-12373. PMID: 37358244
Herein, we have developed nanohybrids (nHs) to remotely activate a therapeutic enzyme for its use in Directed Enzyme Prodrug Therapy (DEPT). The coencapsulation of magnetic nanoparticles (MNPs) with horseradish peroxidase...
4.
Ripoll M, Soriano N, Ibarburu S, Dalies M, Mulet A, Betancor L
Polymers (Basel) . 2023 Jun; 15(11). PMID: 37299313
Bacterial immobilization is regarded as an enabling technology to improve the stability and reusability of biocatalysts. Natural polymers are often used as immobilization matrices but present certain drawbacks, such as...
5.
Ripoll M, Lerma-Escalera J, Morones-Ramirez J, Rios-Solis L, Betancor L
Biotechnol Adv . 2023 Mar; 65:108127. PMID: 36924811
Different from other aerobic microorganisms that oxidise carbon sources to water and carbon dioxide, Gluconobacter catalyses the incomplete oxidation of various substrates with regio- and stereoselectivity. This ability, as well...
6.
Ripoll M, Jackson E, Trelles J, Betancor L
J Biotechnol . 2021 Aug; 340:102-109. PMID: 34454960
In this work, several immobilization strategies for Gluconobacter oxydans NBRC 14819 (Gox) were tested in the bioconversion of crude glycerol to dihydroxyacetone (DHA). Agar, agarose and polyacrylamide were evaluated as...
7.
Umpierrez-Failache M, Abdul Rahim A, Betancor L, Ghoshal S
IEEE Trans Nanobioscience . 2021 Aug; 21(1):157-165. PMID: 34398760
Arsenic (As) is highly toxic in its inorganic form. It is naturally presented at elevated levels in the groundwater of a number of countries and contaminates drinking water sources, generating...
8.
Rivero C, Garcia N, Fernandez-Lucas J, Betancor L, Romanelli G, Trelles J
Biomolecules . 2021 May; 11(5). PMID: 33947162
Nowadays, enzyme-mediated processes offer an eco-friendly and efficient alternative to the traditional multistep and environmentally harmful chemical processes. Herein we report the enzymatic synthesis of cladribine by a novel 2'-deoxyribosyltransferase...
9.
Velasco-Lozano S, Jackson E, Ripoll M, Lopez-Gallego F, Betancor L
Int J Biol Macromol . 2020 Sep; 164:4318-4328. PMID: 32898544
Transaminases are a class of enzymes with promising applications for the preparation and resolution of a vast diversity of valued amines. Their poor operational stability has fueled many investigations on...
10.
Jackson E, Correa S, Betancor L
Methods Mol Biol . 2020 Jan; 2100:259-270. PMID: 31939129
In this chapter we describe different strategies for enzyme immobilization in biomimetic silica nanoparticles. Synthesis of this type of support is performed under mild and biocompatible conditions and has been...