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Lora L Arnold

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Articles 69
Citations 692
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Lima T, Souza N, Ferragut Cardoso A, Gomide L, Nascimento E Pontes M, Miot H, et al.
J Toxicol Pathol . 2022 May; 35(2):159-170. PMID: 35516837
Exposure of Sprague-Dawley (SD) rats to acrylamide (AA) or di-butyl-phthalate (DBP) from the 12th gestational day to the 16th postnatal week (PNW) has been shown to reduce the effectiveness of...
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Ye Z, Abdelmoaty M, Ambardekar V, Curran S, Dyavar S, Arnold L, et al.
Nanomedicine . 2021 Feb; 33():102363. PMID: 33545405
RNA interference molecules have tremendous potential for cancer therapy but are limited by insufficient potency after i.v. administration. We previously found that Chol-DsiRNA polyplexes formed between cholesterol-modified dicer-substrate siRNA (Chol-DsiRNA)...
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Ferragut Cardoso A, Gomide L, Souza N, de Jesus C, Arnold L, Cohen S, et al.
Int J Exp Pathol . 2021 Jan; 102(1):57-69. PMID: 33502821
Cryptorchidism is one of the main risk factors for infertility and testicular cancer. Orchiopexy surgery corrects cryptorchidism effects. Different models of cryptorchidism developed in the rat include surgery. We assessed...
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Suzuki S, Cohen S, Arnold L, Pennington K, Gi M, Kato H, et al.
Toxicol Lett . 2020 Nov; 336:32-38. PMID: 33176187
Tobacco smoking is a major risk factor for human cancers including urinary bladder carcinoma. In a previous study, nicotine enhanced rat urinary bladder carcinogenesis in a two-stage carcinogenesis model. Nicotine...
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Kyoya T, Arnold L, Pennington K, Kakiuchi-Kiyota S, Terada M, Abe K, et al.
Toxicol Mech Methods . 2020 Aug; 30(9):656-671. PMID: 32746684
Pyroxasulfone induced a low incidence of urinary bladder tumors in male rats in a 2-year bioassay at 1000 and 2000 ppm, with occasional urinary calculi. No increased incidence of tumors...
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Suzuki S, Cohen S, Arnold L, Pennington K, Kato H, Naiki T, et al.
Toxicology . 2019 Nov; 429:152325. PMID: 31678612
Tobacco smoking is a major risk factor for human cancers including urinary bladder carcinoma. In a previous study, nicotine enhanced rat urinary bladder carcinogenesis using a rat urinary bladder two-stage...
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Liao Y, Tham D, Liang F, Chang J, Wei Y, Sudhir P, et al.
Mol Biol Cell . 2019 Oct; 30(24):2969-2984. PMID: 31577526
The apical surface of the terminally differentiated mammalian urothelial umbrella cell is mechanically stable and highly impermeable, in part due to its coverage by urothelial plaques consisting of 2D crystals...
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Blevins L, Crawford R, Bach A, Rizzo M, Zhou J, Henriquez J, et al.
Food Chem Toxicol . 2019 Sep; 133:110793. PMID: 31473338
The toxicity of dietary E 171, a food grade titanium dioxide was evaluated. A recent study reported rats receiving E 171 in water developed inflammation and aberrant crypt foci (ACF)...
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Souza N, Arnold L, Pennington K, Nascimento E Pontes M, Miot H, de Camargo J, et al.
Toxicol Mech Methods . 2019 May; 29(7):488-498. PMID: 31050326
The increased incidence of testicular disorders in young men and the possible influence of environmental chemicals, such as dibutyl phthalate (DBP) and acrylamide (AA), requires experimental models for identifying modes...