Longhou Fang
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Explore the profile of Longhou Fang including associated specialties, affiliations and a list of published articles.
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36
Citations
1370
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Recent Articles
1.
Kim J, Jain A, Fang L
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408645
Atherosclerosis, characterized by the accumulation of lipoproteins and lipids within the vascular wall, underlies a heart attack, stroke, and peripheral artery disease. Endothelial inflammation is the primary component driving atherosclerosis,...
2.
Lv J, Meng S, Gu Q, Zheng R, Gao X, Kim J, et al.
Nat Commun
. 2023 May;
14(1):2842.
PMID: 37202413
No abstract available.
3.
Lv J, Meng S, Gu Q, Zheng R, Gao X, Kim J, et al.
Nat Commun
. 2023 May;
14(1):2390.
PMID: 37185814
A comprehensive understanding of endothelial cell lineage specification will advance cardiovascular regenerative medicine. Recent studies found that unique epigenetic signatures preferentially regulate cell identity genes. We thus systematically investigate the...
4.
Kim J, Zhou T, Zhang A, Li S, Gupte A, Hamilton D, et al.
Cells
. 2022 Nov;
11(22).
PMID: 36429071
Accumulating evidence indicates that the APOA1 binding protein (AIBP)-a secreted protein-plays a profound role in lipid metabolism. Interestingly, AIBP also functions as an NAD(P)H-hydrate epimerase to catalyze the interconversion of...
5.
Abe R, Abe J, Nguyen M, Olmsted-Davis E, Mamun A, Banerjee P, et al.
Curr Atheroscler Rep
. 2022 Mar;
24(5):323-336.
PMID: 35332444
Purpose Of Review: As both a cholesterol acceptor and carrier in the reverse cholesterol transport (RCT) pathway, high-density lipoprotein (HDL) is putatively atheroprotective. However, current pharmacological therapies to increase plasma...
6.
Song H, Zhu J, Li P, Han F, Fang L, Yu P
J Biol Chem
. 2021 Sep;
297(4):101149.
PMID: 34473994
Metabolic flexibility is the capacity of cells to alter fuel metabolism in response to changes in metabolic demand or nutrient availability. It is critical for maintaining cellular bioenergetics and is...
7.
Kim J, Zhu L, Sun Q, Fang L
PLoS One
. 2021 Apr;
16(4):e0248964.
PMID: 33793635
Emerging studies indicate that APOA-I binding protein (AIBP) is a secreted protein and functions extracellularly to promote cellular cholesterol efflux, thereby disrupting lipid rafts on the plasma membrane. AIBP is...
8.
Qiu X, Luo J, Fang L
Curr Atheroscler Rep
. 2020 Nov;
23(1):1.
PMID: 33230630
Purpose Of Review: The goal of this manuscript is to summarize the current understanding of the secreted APOA1 binding protein (AIBP), encoded by NAXE, in angiogenesis, hematopoiesis, and inflammation. The...
9.
Zhu L, Parker M, Enemchukwu N, Shen M, Zhang G, Yan Q, et al.
Commun Biol
. 2020 Jul;
3(1):386.
PMID: 32678293
Many patients of choroidal neovascularization (CNV) are unresponsive to the current anti-VEGF treatment. The mechanisms for anti-VEGF resistance are poorly understood. We explore the unique property of the apolipoprotein A-I...
10.
Morgan P, Fang L, Lancaster G, Murphy A
J Lipid Res
. 2019 Sep;
61(5):667-675.
PMID: 31471447
Lipid rafts are highly ordered regions of the plasma membrane that are enriched in cholesterol and sphingolipids and play important roles in many cells. In hematopoietic stem and progenitor cells...