Long Vo Ngoc
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Explore the profile of Long Vo Ngoc including associated specialties, affiliations and a list of published articles.
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9
Citations
472
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Recent Articles
1.
Vo Ngoc L, Rhyne T, Kadonaga J
Genes Dev
. 2023 May;
37(9-10):377-382.
PMID: 37163335
The RNA polymerase II core promoter is the site of convergence of the signals that lead to the initiation of transcription. Here, we performed a comparative analysis of the downstream...
2.
Vo Ngoc L, Huang C, Cassidy C, Medrano C, Kadonaga J
Nature
. 2020 Sep;
585(7825):459-463.
PMID: 32908305
The RNA polymerase II (Pol II) core promoter is the strategic site of convergence of the signals that lead to the initiation of DNA transcription, but the downstream core promoter...
3.
Vo Ngoc L, Kassavetis G, Kadonaga J
Genetics
. 2019 May;
212(1):13-24.
PMID: 31053615
Transcription by RNA polymerase II initiates at the core promoter, which is sometimes referred to as the "gateway to transcription." Here, we describe the properties of the RNA polymerase II...
4.
de Toeuf B, Soin R, Nazih A, Dragojevic M, Jurenas D, Delacourt N, et al.
Sci Rep
. 2018 Mar;
8(1):5211.
PMID: 29581565
Hypoxia triggers profound modifications of cellular transcriptional programs. Upon reoxygenation, cells return to a normoxic gene expression pattern and mRNA produced during the hypoxic phase are degraded. TIS11 proteins control...
5.
Vo Ngoc L, Wang Y, Kassavetis G, Kadonaga J
Genes Dev
. 2017 Aug;
31(13):1289-1301.
PMID: 28808065
The signals that direct the initiation of transcription ultimately converge at the core promoter, which is the gateway to transcription. Here we provide an overview of the RNA polymerase II...
6.
Vo Ngoc L, Cassidy C, Huang C, Duttke S, Kadonaga J
Genes Dev
. 2017 Jan;
31(1):6-11.
PMID: 28108474
DNA sequence signals in the core promoter, such as the initiator (Inr), direct transcription initiation by RNA polymerase II. Here we show that the human Inr has the consensus of...
7.
Delatte B, Wang F, Vo Ngoc L, Collignon E, Bonvin E, Deplus R, et al.
Science
. 2016 Jan;
351(6270):282-5.
PMID: 26816380
Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophila. We map the transcriptome-wide hydroxymethylation...
8.
Vo Ngoc L, Wauquier C, Soin R, Bousbata S, Twyffels L, Kruys V, et al.
Mol Cell Biol
. 2014 Sep;
34(23):4315-28.
PMID: 25246635
The TIS11/tristetraprolin (TTP) CCCH tandem zinc finger proteins are major effectors in the destabilization of mRNAs bearing AU-rich elements (ARE) in their 3' untranslated regions. In this report, we demonstrate...
9.
Vindry C, Vo Ngoc L, Kruys V, Gueydan C
Biochem Pharmacol
. 2014 Apr;
89(4):431-40.
PMID: 24735612
Initially identified as an occasional and peculiar mode of gene regulation in eukaryotes, RNA-binding protein-mediated post-transcriptional control of gene expression has emerged, over the last two decades, as a major...