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Lise Barbe

Explore the profile of Lise Barbe including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 116
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Recent Articles
1.
Barbe L, Lam S, Holub A, Faghihmonzavi Z, Deng M, Iyer R, et al.
Redox Biol . 2023 Mar; 62:102680. PMID: 37001328
DNA damage is a common cellular feature seen in cancer and neurodegenerative disease, but fast and accurate methods for quantifying DNA damage are lacking. Comet assays are a biochemical tool...
2.
Barbe L, Finkbeiner S
Front Aging Neurosci . 2022 May; 14:750629. PMID: 35592702
Repeat diseases, such as fragile X syndrome, myotonic dystrophy, Friedreich ataxia, Huntington disease, spinocerebellar ataxias, and some forms of amyotrophic lateral sclerosis, are caused by repetitive DNA sequences that are...
3.
Franck S, Couvreu de Deckersberg E, Bubenik J, Markouli C, Barbe L, Allemeersch J, et al.
Biol Open . 2022 Jan; 11(1). PMID: 35019138
Skeletal muscle tissue is severely affected in myotonic dystrophy type 1 (DM1) patients, characterised by muscle weakness, myotonia and muscle immaturity in the most severe congenital form of the disease....
4.
Franck S, Barbe L, Ardui S, De Vlaeminck Y, Allemeersch J, Dziedzicka D, et al.
Hum Mol Genet . 2020 Nov; 29(21):3566-3577. PMID: 33242073
Myotonic dystrophy type 1 (DM1) is caused by expansion of a CTG repeat in the DMPK gene, where expansion size and somatic mosaicism correlates with disease severity and age of...
5.
Barbe L, Lanni S, Lopez-Castel A, Franck S, Spits C, Keymolen K, et al.
Am J Hum Genet . 2017 Mar; 100(3):488-505. PMID: 28257691
CTG repeat expansions in DMPK cause myotonic dystrophy (DM1) with a continuum of severity and ages of onset. Congenital DM1 (CDM1), the most severe form, presents distinct clinical features, large...
6.
Dziedzicka D, Markouli C, Barbe L, Spits C, Sermon K, Geens M
Stem Cell Rev Rep . 2016 Aug; 12(6):721-730. PMID: 27544201
When aiming for homogenous embryoid body (EB) differentiation, the use of equal-sized EBs is required to avoid a size-induced differentiation bias. In this study we developed an efficient and standardized...
7.
Jacobs K, Zambelli F, Mertzanidou A, Smolders I, Geens M, Nguyen H, et al.
Stem Cell Reports . 2016 Mar; 6(3):330-41. PMID: 26923824
Human embryonic stem cells (hESC) show great promise for clinical and research applications, but their well-known proneness to genomic instability hampers the development to their full potential. Here, we demonstrate...
8.
Nguyen H, Markouli C, Geens M, Barbe L, Sermon K, Spits C
Mol Hum Reprod . 2014 Aug; 20(10):981-9. PMID: 25082980
It is well known that human embryonic stem cells (hESCs) frequently acquire recurrent chromosomal abnormalities, very reminiscent of those found in cancerous cells. Given the parallels between cancer and stem...