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Lisandra Herrera Belen

Explore the profile of Lisandra Herrera Belen including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 162
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Recent Articles
1.
Beltran J, Belen L, Yanez A, Jimenez L
BMC Bioinformatics . 2024 Nov; 25(1):351. PMID: 39522017
Viral proteins that evade the host's innate immune response play a crucial role in pathogenesis, significantly impacting viral infections and potential therapeutic strategies. Identifying these proteins through traditional methods is...
2.
Tosta Perez M, Belen L, Pessoa A, Avendano J
Curr Drug Saf . 2024 Jul; PMID: 39075954
L-asparaginase (L-ASNase) is an enzyme that shows targeted activity against Acute Lymphoblastic Leukemia (ALL) and similar lymphoid neoplasms by facilitating the breakdown of asparagine into L-aspartic acid, thereby reducing L-asparagine...
3.
Herrera-Bravo J, Belen L, Reyes M, Silva V, Fuentealba S, Paz C, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2024 Jun; 397(11):8259-8284. PMID: 38847831
Cancer remains a global health challenge, prompting a search for effective treatments with fewer side effects. Thymol, a natural monoterpenoid phenol derived primarily from thyme (Thymus vulgaris) and other plants...
4.
Beltran J, Belen L, Farias J, Zamorano M, Lefin N, Miranda J, et al.
Brief Bioinform . 2023 Nov; 25(1). PMID: 38033292
Throughout evolution, pathogenic viruses have developed different strategies to evade the response of the adaptive immune system. To carry out successful replication, some pathogenic viruses encode different proteins that manipulate...
5.
Miranda J, Lefin N, Beltran J, Belen L, Tsipa A, Farias J, et al.
BioDrugs . 2023 Sep; 37(6):793-811. PMID: 37698749
Over the past few years, there has been a surge in the industrial production of recombinant enzymes from microorganisms due to their catalytic characteristics being highly efficient, selective, and biocompatible....
6.
Lefin N, Miranda J, Beltran J, Belen L, Effer B, Pessoa Jr A, et al.
Front Pharmacol . 2023 Jul; 14:1208277. PMID: 37426818
Heterologous expression of L-asparaginase (L-ASNase) has become an important area of research due to its clinical and food industry applications. This review provides a comprehensive overview of the molecular and...
7.
Pedroso A, Belen L, Beltran J, Castillo R, Pessoa A, Pedroso E, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108713
Acute lymphoblastic leukemia (ALL) is the most common cancer among children worldwide, characterized by an overproduction of undifferentiated lymphoblasts in the bone marrow. The treatment of choice for this disease...
8.
Tosta Perez M, Belen L, Letelier P, Calle Y, Pessoa A, Farias J
Med Oncol . 2023 Apr; 40(5):150. PMID: 37060469
L-Asparaginase is an antileukemic drug long approved for clinical use to treat childhood acute lymphoblastic leukemia, the most common cancer in this population worldwide. However, the efficacy and its use...
9.
Belen L, Beltran J, Pessoa Jr A, Castillo R, Rangel-Yagui C, Farias J
3 Biotech . 2022 Oct; 12(11):286. PMID: 36276451
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-022-03359-0.
10.
Silva A, Guimaraes M, Rabelo J, Belen L, Perecin C, Farias J, et al.
J Mater Chem B . 2022 Mar; 10(19):3587-3600. PMID: 35262120
Antimicrobial peptides (AMPs) are ubiquitous host defense peptides characterized by their antibiotic activity and lower propensity for developing resistance compared to classic antibiotics. While several AMPs have shown activity against...