Lisa M Coussens
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Explore the profile of Lisa M Coussens including associated specialties, affiliations and a list of published articles.
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29582
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Recent Articles
11.
Phillips E, Alharithi Y, Kadam L, Coussens L, Kumar S, Maloyan A
bioRxiv
. 2023 Dec;
PMID: 38077037
Intrauterine metabolic reprogramming occurs in obese mothers during gestation, putting the offspring at high risk of developing obesity and associated metabolic disorders even before birth. We have generated a mouse...
12.
Blise K, Sivagnanam S, Betts C, Betre K, Kirchberger N, Tate B, et al.
bioRxiv
. 2023 Nov;
PMID: 37961410
Tumor molecular datasets are becoming increasingly complex, making it nearly impossible for humans alone to effectively analyze them. Here, we demonstrate the power of using machine learning to analyze a...
13.
Johnson J, Stein-OBrien G, Booth M, Heiland R, Kurtoglu F, Bergman D, et al.
bioRxiv
. 2023 Sep;
PMID: 37745323
Cells are fundamental units of life, constantly interacting and evolving as dynamical systems. While recent spatial multi-omics can quantitate individual cells' characteristics and regulatory programs, forecasting their evolution ultimately requires...
14.
Kim E, Chen P, Bressan D, Tripathi M, Miremadi A, di Pietro M, et al.
Cell Rep Methods
. 2023 Sep;
3(10):100595.
PMID: 37741277
Imaging mass cytometry (IMC) is a powerful technique capable of detecting over 30 markers on a single slide. It has been increasingly used for single-cell-based spatial phenotyping in a wide...
15.
Doha Z, Wang X, Calistri N, Eng J, Daniel C, Ternes L, et al.
Nat Commun
. 2023 Sep;
14(1):5665.
PMID: 37704631
Triple-negative breast cancer (TNBC) patients have a poor prognosis and few treatment options. Mouse models of TNBC are important for development of new therapies, however, few mouse models represent the...
16.
Gurun B, Horton W, Murugan D, Zhu B, Leyshock P, Kumar S, et al.
BMC Genomics
. 2023 Jun;
24(1):349.
PMID: 37365517
T cell receptor repertoires can be profiled using next generation sequencing (NGS) to measure and monitor adaptive dynamical changes in response to disease and other perturbations. Genomic DNA-based bulk sequencing...
17.
Coussens L, de Palma M, Mariani S, Cassetta L
Nat Rev Cancer
. 2023 Jun;
23(8):507.
PMID: 37353680
No abstract available.
18.
Anczukow O, Airhart S, Chuang J, Coussens L, Kuchel G, Korstanje R, et al.
Cancer Cell
. 2023 Mar;
41(4):641-645.
PMID: 37001528
Age is among the main risk factors for cancer, and any cancer study in adults is faced with an aging tissue and organism. Yet, pre-clinical studies are carried out using...
19.
Ren T, Chen C, Danilov A, Liu S, Guan X, Du S, et al.
bioRxiv
. 2023 Mar;
PMID: 36993424
Accurately identifying phenotype-relevant cell subsets from heterogeneous cell populations is crucial for delineating the underlying mechanisms driving biological or clinical phenotypes. Here, by deploying a learning with rejection strategy, we...
20.
Steele M, Jaiswal A, Delclaux I, Dryg I, Murugan D, Femel J, et al.
Nat Immunol
. 2023 Mar;
24(4):729.
PMID: 36932125
No abstract available.