Lisa C Laan
Overview
Explore the profile of Lisa C Laan including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
187
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Recent Articles
1.
Stavenhagen K, Laan L, Gao C, Mehta A, Heimburg-Molinaro J, Glickman J, et al.
Cell Mol Life Sci
. 2021 Jun;
78(14):5569-5585.
PMID: 34089345
The macrophage mannose receptor (CD206, MR) is an endocytic lectin receptor which plays an important role in homeostasis and innate immunity, however, the endogenous glycan and glycoprotein ligands recognized by...
2.
Zhang T, Van Die I, Tefsen B, van Vliet S, Laan L, Zhang J, et al.
Front Oncol
. 2020 Jun;
10:732.
PMID: 32582529
Changes in the glycosylation profile of cancer cells have been strongly associated with cancer progression. To increase our insights into the role of glycosylation in human pancreatic ductal adenocarcinoma (PDAC),...
3.
Wolde M, Laan L, Medhin G, Gadissa E, Berhe N, Tsegaye A
J Inflamm Res
. 2020 Feb;
13:35-43.
PMID: 32021377
Introduction: Epidemiological and animal studies indicate that helminth infections have positive effects due to their potential to protect against autoimmune diseases. Here, we aim to assess the effect of infection...
4.
Minato K, Laan L, Van Die I, Mizuno M
Int J Biol Macromol
. 2018 Nov;
122:705-712.
PMID: 30392853
Polysaccharides from edible mushrooms possess important immunomodulating effects on immune cells including monocytes and macrophages. Macrophages activated by LPS/IFNγ are polarized toward inflammatory macrophages, whereas the anti-inflammatory properties of alternative...
5.
Williams A, Klaver E, Laan L, Ramsay A, Fryganas C, Difborg R, et al.
Immunology
. 2016 Dec;
150(3):312-328.
PMID: 27905107
Interactions between dendritic cells (DCs) and environmental, dietary and pathogen antigens play a key role in immune homeostasis and regulation of inflammation. Dietary polyphenols such as proanthocyanidins (PAC) may reduce...
6.
Laan L, Williams A, Stavenhagen K, Giera M, Kooij G, Vlasakov I, et al.
FASEB J
. 2016 Nov;
31(2):719-731.
PMID: 27806992
Clinical trials have shown that administration of the nematode Trichuris suis can be beneficial in treating various immune disorders. To provide insight into the mechanisms by which this worm suppresses...
7.
Minato K, Laan L, Ohara A, Van Die I
Int Immunopharmacol
. 2016 Sep;
40:156-163.
PMID: 27592080
Many edible mushrooms have become attractive as "health foods" and as source materials for immunomodulators. To increase our insight in the immune-modulatory properties of a polysaccharide of the oyster mushroom...
8.
Hoeksema M, Laan L, Postma J, Cummings R, de Winther M, Dijkstra C, et al.
FASEB J
. 2016 Apr;
30(8):2826-36.
PMID: 27095802
Helminths have strong immunoregulatory properties that may be exploited in treatment of chronic immune disorders, such as multiple sclerosis and inflammatory bowel disease. Essential players in the pathogenesis of these...
9.
Belo A, van Vliet S, Maus A, Laan L, Nauta T, Koolwijk P, et al.
FEBS Lett
. 2015 Aug;
589(18):2359-66.
PMID: 26232512
The α1,2-fucosyltransferase activity in pancreatic tumors is much lower compared to normal pancreatic tissue. Here we show that hypoxia inducible factor (HIF) 1α is constitutively expressed in the pancreatic cancer...
10.
Kooij G, Braster R, Koning J, Laan L, van Vliet S, Los T, et al.
Acta Neuropathol Commun
. 2015 Jul;
3:45.
PMID: 26205402
Introduction: The inverse correlation between prevalence of auto-immune disorders like the chronic neuro-inflammatory disease multiple sclerosis (MS) and the occurrence of helminth (worm) infections, suggests that the helminth-trained immune system...