Christine D Dijkstra
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Explore the profile of Christine D Dijkstra including associated specialties, affiliations and a list of published articles.
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64
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3104
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Recent Articles
1.
Aarts S, Seijkens T, van Dorst K, Dijkstra C, Kooij G, Lutgens E
Front Immunol
. 2018 Jan;
8:1791.
PMID: 29312317
The CD40-CD40L dyad is an immune checkpoint regulator that promotes both innate and adaptive immune responses and has therefore an essential role in the development of inflammatory diseases, including multiple...
2.
Malinova T, Dijkstra C, de Vries H
Mult Scler
. 2017 Nov;
24(9):1144-1150.
PMID: 29117778
Background: The significance of the gut microbiome for the pathogenesis of multiple sclerosis (MS) has been established, although the underlying signaling mechanisms of this interaction have not been sufficiently explored....
3.
Aarts S, Seijkens T, Kusters P, van der Pol S, Zarzycka B, Heijnen P, et al.
J Neuroinflammation
. 2017 May;
14(1):105.
PMID: 28494768
Background: The influx of leukocytes into the central nervous system (CNS) is a key hallmark of the chronic neuro-inflammatory disease multiple sclerosis (MS). Strategies that aim to inhibit leukocyte migration...
4.
Laan L, Williams A, Stavenhagen K, Giera M, Kooij G, Vlasakov I, et al.
FASEB J
. 2016 Nov;
31(2):719-731.
PMID: 27806992
Clinical trials have shown that administration of the nematode Trichuris suis can be beneficial in treating various immune disorders. To provide insight into the mechanisms by which this worm suppresses...
5.
Hoeksema M, Laan L, Postma J, Cummings R, de Winther M, Dijkstra C, et al.
FASEB J
. 2016 Apr;
30(8):2826-36.
PMID: 27095802
Helminths have strong immunoregulatory properties that may be exploited in treatment of chronic immune disorders, such as multiple sclerosis and inflammatory bowel disease. Essential players in the pathogenesis of these...
6.
Kooij G, Braster R, Koning J, Laan L, van Vliet S, Los T, et al.
Acta Neuropathol Commun
. 2015 Jul;
3:45.
PMID: 26205402
Introduction: The inverse correlation between prevalence of auto-immune disorders like the chronic neuro-inflammatory disease multiple sclerosis (MS) and the occurrence of helminth (worm) infections, suggests that the helminth-trained immune system...
7.
Yildirim C, Vogel D, Hollander M, Baggen J, Fontijn R, Nieuwenhuis S, et al.
PLoS One
. 2015 Apr;
10(4):e0124347.
PMID: 25884209
Galectin-2 is a monocyte-expressed carbohydrate-binding lectin, for which increased expression is genetically determined and associated with decreased collateral arteriogenesis in obstructive coronary artery disease patients. The inhibiting effect of galectin-2...
8.
Vogel D, Kooij G, Heijnen P, Breur M, Peferoen L, van der Valk P, et al.
Eur J Immunol
. 2015 Mar;
45(6):1808-19.
PMID: 25756873
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Infiltration of monocytes into the CNS is crucial for disease onset and progression. Animal studies...
9.
Peferoen L, Vogel D, Ummenthum K, Breur M, Heijnen P, Gerritsen W, et al.
J Neuropathol Exp Neurol
. 2014 Dec;
74(1):48-63.
PMID: 25470347
Similar to macrophages, microglia adopt diverse activation states and contribute to repair and tissue damage in multiple sclerosis. Using reverse transcription-quantitative polymerase chain reaction and immunohistochemistry, we show that in...
10.
Sawanobori Y, Ueta H, Dijkstra C, Park C, Satou M, Kitazawa Y, et al.
PLoS One
. 2014 Oct;
9(10):e109995.
PMID: 25334032
Aim: Thymic epithelial cells (TECs) are thought to play an essential role in T cell development and have been detected mainly in mice using lectin binding and antibodies to keratins....