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Lirong Pei

Explore the profile of Lirong Pei including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 552
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Recent Articles
1.
Ding Z, Shi H, Aboelella N, Fesenkova K, Park E, Liu Z, et al.
Sci Immunol . 2020 Oct; 5(52). PMID: 33127608
The presence of polyfunctional CD4 T cells is often associated with favorable antitumor immunity. We report here that persistent activation of signal transducer and activator of transcription 5 (STAT5) in...
2.
Guo C, Pei L, Xiao X, Wei Q, Chen J, Ding H, et al.
Kidney Int . 2017 Jul; 92(5):1194-1205. PMID: 28709638
DNA methylation is an epigenetic mechanism that regulates gene transcription without changing primary nucleotide sequences. In mammals, DNA methylation involves the covalent addition of a methyl group to the 5-carbon...
3.
Noonepalle S, Gu F, Lee E, Choi J, Han Q, Kim J, et al.
Cancer Immunol Res . 2017 Mar; 5(4):330-344. PMID: 28264810
Triple-negative breast cancer (TNBC) cells are modulated in reaction to tumor-infiltrating lymphocytes. However, their specific responses to this immune pressure are unknown. In order to address this question, we first...
4.
Wu J, Xu X, Lee E, Shull A, Pei L, Awan F, et al.
Oncotarget . 2016 Jun; 7(26):40558-40570. PMID: 27302925
Immunosuppression is a prevalent clinical feature in chronic lymphocytic leukemia (CLL) patients, with many patients demonstrating increased susceptibility to infections as well as increased failure of an antitumor immune response....
5.
Lee E, Rath P, Liu J, Ryu D, Pei L, Noonepalle S, et al.
J Genet Genomics . 2015 Aug; 42(7):355-71. PMID: 26233891
Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. The existence of a small population of stem-like tumor cells that efficiently propagate tumors and resist...
6.
Shull A, Noonepalle S, Awan F, Liu J, Pei L, Bollag R, et al.
Oncotarget . 2015 May; 6(16):14632-45. PMID: 25999352
Chronic lymphocytic leukemia (CLL), the most common adult leukemia, remains incurable despite advancements in treatment regimens over the past decade. Several expression profile studies have been pursued to better understand...
7.
Pathania R, Ramachandran S, Elangovan S, Padia R, Yang P, Cinghu S, et al.
Nat Commun . 2015 Apr; 6:6910. PMID: 25908435
Mammary stem/progenitor cells (MaSCs) maintain self-renewal of the mammary epithelium during puberty and pregnancy. DNA methylation provides a potential epigenetic mechanism for maintaining cellular memory during self-renewal. Although DNA methyltransferases...
8.
Liu Z, Zhang J, Gao Y, Pei L, Zhou J, Gu L, et al.
Clin Cancer Res . 2014 Jul; 20(17):4598-612. PMID: 25009298
Purpose: Metastasis is the leading cause of death for gastric carcinoma. An epigenetic biomarker panel for predicting gastric carcinoma metastasis could have significant clinical impact on the care of patients...
9.
Luo D, Wilson J, Harvel N, Liu J, Pei L, Huang S, et al.
J Transl Med . 2013 Mar; 11:57. PMID: 23497265
In this study we performed a systematic evaluation of functional miRNA-mRNA interactions associated with the invasiveness of breast cancer cells using a combination of integrated miRNA and mRNA expression profiling,...
10.
Pei L, Choi J, Liu J, Lee E, McCarthy B, Wilson J, et al.
Epigenetics . 2012 Apr; 7(6):567-78. PMID: 22534504
We conducted a genome-wide DNA methylation analysis in CD19 (+) B-cells from chronic lymphocytic leukemia (CLL) patients and normal control samples using reduced representation bisulfite sequencing (RRBS). The methylation status...