Linzhang Huang
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Explore the profile of Linzhang Huang including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
404
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0
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Recent Articles
1.
Zhang X, Jia A, You J, Zhuang Z, Wang Y, Liu T, et al.
Haematologica
. 2025 Jan;
PMID: 39781620
Not available.
2.
Li Y, Liao J, Xiong L, Xiao Z, Ye F, Wang Y, et al.
J Control Release
. 2024 Feb;
368:607-622.
PMID: 38423472
Ischemia-reperfusion injury is caused by excessive production of reactive oxygen species (ROS) and inflammation accompanied by ischemic injury symptoms and blood-brain barrier (BBB) dysfunction. This causes neuronal damage, for which...
3.
Peng J, Yu L, Huang L, Paschoal V, Chu H, de Souza C, et al.
Mol Metab
. 2023 Sep;
78:101812.
PMID: 37777009
Objective: Sialic acid is a terminal monosaccharide of glycans in glycoproteins and glycolipids, and its derivation from glucose is regulated by the rate-limiting enzyme UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE). Although the...
4.
Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh H, et al.
Nat Commun
. 2023 Jul;
14(1):4101.
PMID: 37491347
Hypercholesterolemia and vascular inflammation are key interconnected contributors to the pathogenesis of atherosclerosis. How hypercholesterolemia initiates vascular inflammation is poorly understood. Here we show in male mice that hypercholesterolemia-driven endothelial...
5.
Cardoso A, Lam N, Savla J, Nakada Y, Pereira A, Elnwasany A, et al.
Nat Metab
. 2020 Jul;
2(2):167-178.
PMID: 32617517
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides...
6.
Khan H, Nair V, Ruhl C, Alvarez-Arguedas S, Galvan Rendiz J, Franco L, et al.
Elife
. 2020 Mar;
9.
PMID: 32134383
(Mtb) can enter the body through multiple routes, including via specialized transcytotic cells called microfold cells (M cell). However, the mechanistic basis for M cell entry remains undefined. Here, we...
7.
Huang L, Chambliss K, Gao X, Yuhanna I, Behling-Kelly E, Bergaya S, et al.
Nature
. 2019 Apr;
569(7757):565-569.
PMID: 31019307
Atherosclerosis, which underlies life-threatening cardiovascular disorders such as myocardial infarction and stroke, is initiated by passage of low-density lipoprotein (LDL) cholesterol into the artery wall and its engulfment by macrophages,...
8.
Chambliss K, Barrera J, Umetani M, Umetani J, Kim S, Madak-Erdogan Z, et al.
Endocrinology
. 2016 Aug;
157(10):3731-3741.
PMID: 27552247
Estrogens have the potential to afford atheroprotection, to prevent excess adiposity and its metabolic complications including insulin resistance, and to lessen hepatic steatosis. Cellular responses to estrogens occur through gene...
9.
Ding Y, Huang L, Xian X, Yuhanna I, Wasser C, Frotscher M, et al.
Sci Signal
. 2016 Mar;
9(419):ra29.
PMID: 26980442
The multimodular glycoprotein Reelin controls neuronal migration and synaptic transmission by binding to apolipoprotein E receptor 2 (Apoer2) and very low density lipoprotein receptor (Vldlr) on neurons. In the periphery,...
10.
Huang L, Fan B, Ma A, Shaul P, Zhu H
J Lipid Res
. 2015 Mar;
56(5):986-97.
PMID: 25761370
ABCA1 plays a key role in the initial lipidation of apoA-I, which generates circulating HDL cholesterol. Whereas it is known that the transcriptional upregulation of ABCA1 promotes HDL formation and...