Linnea Asp
Overview
Explore the profile of Linnea Asp including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
683
Followers
0
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Recent Articles
1.
Dutta D, Zameer A, Mariani J, Zhang J, Asp L, Huynh J, et al.
Development
. 2018 Jul;
145(13).
PMID: 30006479
No abstract available.
2.
Laitman B, Asp L, Mariani J, Zhang J, Liu J, Sawai S, et al.
PLoS Biol
. 2016 May;
14(5):e1002467.
PMID: 27213272
Growth factors of the gp130 family promote oligodendrocyte differentiation, and viability, and myelination, but their mechanisms of action are incompletely understood. Here, we show that these effects are coordinated, in...
3.
Chapouly C, Argaw A, Horng S, Castro K, Zhang J, Asp L, et al.
Brain
. 2015 Mar;
138(Pt 6):1548-67.
PMID: 25805644
In inflammatory central nervous system conditions such as multiple sclerosis, breakdown of the blood-brain barrier is a key event in lesion pathogenesis, predisposing to oedema, excitotoxicity, and ingress of plasma...
4.
Dutta D, Zameer A, Mariani J, Zhang J, Asp L, Huynh J, et al.
Development
. 2014 Jun;
141(12):2414-28.
PMID: 24917498
In the embryonic CNS, development of myelin-forming oligodendrocytes is limited by bone morphogenetic proteins, which constitute one arm of the transforming growth factor-β (Tgfβ) family and signal canonically via Smads...
5.
Liu X, Holtze M, Powell S, Terrando N, Larsson M, Persson A, et al.
Brain Behav Immun
. 2013 Oct;
36:80-9.
PMID: 24140727
Exposure to infections in early life is considered a risk-factor for developing schizophrenia. Recently we reported that a neonatal CNS infection with influenza A virus in mice resulted in a...
6.
Johansson A, Owe-Larsson B, Asp L, Kocki T, Adler M, Hetta J, et al.
J Psychiatr Res
. 2013 Sep;
47(11):1815-23.
PMID: 24012176
Accumulating data suggest a causative link between immune stimulation, disturbed metabolism of tryptophan, and pathogenesis of bipolar disorder and schizophrenia. The goal of this study was to examine the production...
7.
Argaw A, Asp L, Zhang J, Navrazhina K, Pham T, Mariani J, et al.
J Clin Invest
. 2012 Jun;
122(7):2454-68.
PMID: 22653056
In inflammatory CNS conditions such as multiple sclerosis (MS), current options to treat clinical relapse are limited, and more selective agents are needed. Disruption of the blood-brain barrier (BBB) is...
8.
Asp L, Johansson A, Mann A, Owe-Larsson B, Urbanska E, Kocki T, et al.
J Inflamm (Lond)
. 2011 Oct;
8:25.
PMID: 21982155
Background: The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites. Altered levels of KP-metabolites have been observed...
9.
Zhang J, Kramer E, Asp L, Dutta D, Navrazhina K, Pham T, et al.
FEBS Lett
. 2011 Aug;
585(23):3813-20.
PMID: 21864535
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Conduction block in demyelinated axons underlies early neurological symptoms, but axonal transection and neuronal loss are believed to be...
10.
Asp L, Holtze M, Powell S, Karlsson H, Erhardt S
Int J Neuropsychopharmacol
. 2009 Jul;
13(4):475-85.
PMID: 19607757
Epidemiological studies suggest that early life infections may contribute to the development of neuropsychiatric disorders later in life. Experimental studies employing infections during neonatal life support this notion by reporting...