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Lingli He

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Citations 963
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Recent Articles
1.
Fukushima T, Kristiansen T, Wong L, Keyes S, Tanaka Y, Mazzola M, et al.
bioRxiv . 2025 Mar; PMID: 40027782
Transitions between subsets of differentiating hematopoietic cells are widely regarded as unidirectional . Here, we introduce clonal phylogenetic tracer (CP-tracer) that sequentially introduces genetic barcodes, enabling high-resolution analysis of ~100,000...
2.
He L, Zhao T, Leong W, Sharda A, Mayerhofer C, Mei S, et al.
Blood . 2025 Feb; PMID: 39912669
Differentiation arrest and dependence on oxidative metabolism are features shared among genetically diverse acute myeloid leukemias (AML). A phenotypic CRISPR-Cas9 screen in AML identified dependence on phosphoseryl-tRNA kinase (PSTK), an...
3.
Qian F, Liu Y, He L, Dong Z, Chen M, Liu W
J Environ Manage . 2024 Jul; 366:121797. PMID: 38996605
To overcome the significant challenges associated with nitrite supply and nitrate residues in mainstream anaerobic ammonium oxidation (anammox)-based processes, this study developed a combined solid-phase denitrification (SPD) and anammox process...
4.
de Back T, Wu T, Schafrat P, Ten Hoorn S, Tan M, He L, et al.
Life Sci Alliance . 2024 Jun; 7(9). PMID: 38936972
No abstract available.
5.
de Back T, Wu T, Schafrat P, Ten Hoorn S, Tan M, He L, et al.
Life Sci Alliance . 2024 May; 7(8). PMID: 38782602
Consensus Molecular Subtype (CMS) classification of colorectal cancer (CRC) tissues is complicated by RNA degradation upon formalin-fixed paraffin-embedded (FFPE) preservation. Here, we present an FFPE-curated CMS classifier. The CMSFFPE classifier...
6.
Wu M, Hu L, He L, Yuan L, Yang L, Zhao B, et al.
J Biol Chem . 2024 Mar; 300(5):107212. PMID: 38522513
As an output effector of the Hippo signaling pathway, the TEAD transcription factor and co-activator YAP play crucial functions in promoting cell proliferation and organ size. The tumor suppressor NF2...
7.
Li J, He L, Zhang X, Li X, Wang L, Zhu Z, et al.
Comput Struct Biotechnol J . 2024 Feb; 23:752-758. PMID: 38304548
Gastric cancer (GC) is one of the most commonly diagnosed malignancies, threatening millions of lives worldwide each year. Importantly, GC is a heterogeneous disease, posing a significant challenge to the...
8.
Dong Y, Yu Z, Li Y, Huang B, Bai Q, Gao Y, et al.
EMBO J . 2024 Jan; 43(1):14-31. PMID: 38177313
Sodium-calcium exchanger proteins influence calcium homeostasis in many cell types and participate in a wide range of physiological and pathological processes. Here, we elucidate the cryo-EM structure of the human...
9.
Wang Y, Pan C, Chen Q, Xie Q, Gao Y, He L, et al.
Nat Commun . 2023 Jul; 14(1):4487. PMID: 37495621
Salt-overly-sensitive 1 (SOS1) is a unique electroneutral Na/H antiporter at the plasma membrane of higher plants and plays a central role in resisting salt stress. SOS1 is kept in a...
10.
Yan F, Wang S, Huang Z, Liu Y, He L, Qian F
Environ Res . 2023 Mar; 226:115701. PMID: 36931374
Granular sludges are commonly microbial aggregates used to apply partial nitritation/anammox (PN/A) processes during efficient biological nitrogen removal from ammonium-rich wastewater. Considering keystone taxa of anammox bacteria (AnAOB) in granules...