Lindsay B McKenna
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Explore the profile of Lindsay B McKenna including associated specialties, affiliations and a list of published articles.
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7
Citations
582
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Recent Articles
1.
Ferreira M, McKenna L, Zhang J, Reichert M, Bakir B, Buza E, et al.
Cell Mol Gastroenterol Hepatol
. 2016 Jan;
1(5):550-569.
PMID: 26740970
Background & Aims: Perturbations in pancreatic ductal bicarbonate secretion cause chronic pancreatitis. The physiologic mechanism of ductal secretion is known, but its transcriptional control is not. We determine the role...
2.
Zhang J, McKenna L, Bogue C, Kaestner K
Genes Dev
. 2014 Apr;
28(8):829-34.
PMID: 24736842
The homeodomain transcription factor HHEX (hematopoietically expressed homeobox) has been repeatedly linked to type 2 diabetes mellitus (T2DM) using genome-wide association studies. We report here that within the adult endocrine...
3.
Kameswaran V, Bramswig N, McKenna L, Penn M, Schug J, Hand N, et al.
Cell Metab
. 2013 Dec;
19(1):135-45.
PMID: 24374217
Type 2 diabetes mellitus (T2DM) is a complex disease characterized by the inability of the insulin-producing β cells in the endocrine pancreas to overcome insulin resistance in peripheral tissues. To...
4.
Schug J, McKenna L, Walton G, Hand N, Mukherjee S, Essuman K, et al.
BMC Genomics
. 2013 Apr;
14:264.
PMID: 23597149
Background: Validation of physiologic miRNA targets has been met with significant challenges. We employed HITS-CLIP to identify which miRNAs participate in liver regeneration, and to identify their target mRNAs. Results:...
5.
Gao Y, Schug J, McKenna L, Le Lay J, Kaestner K, Greenbaum L
Nucleic Acids Res
. 2010 Sep;
39(2):454-63.
PMID: 20843784
MicroRNAs fine-tune the activity of hundreds of protein-coding genes. The identification of tissue-specific microRNAs and their promoters has been constrained by the limited sensitivity of prior microRNA quantification methods. Here,...
6.
McKenna L, Schug J, Vourekas A, McKenna J, Bramswig N, Friedman J, et al.
Gastroenterology
. 2010 Jul;
139(5):1654-64, 1664.e1.
PMID: 20659473
Background & Aims: Whereas the importance of microRNA (miRNA) for the development of several tissues is well established, its role in the intestine is unknown. We aimed to quantify the...
7.
Madison B, McKenna L, Dolson D, Epstein D, Kaestner K
J Biol Chem
. 2008 Dec;
284(9):5936-44.
PMID: 19049965
The hedgehog (Hh) signaling pathway is a key component of cross-talk during vertebrate gut development, involving endodermally secreted Sonic (Shh) and Indian hedgehog (Ihh) proteins that directly signal to adjacent...