Linda M Parsons
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Explore the profile of Linda M Parsons including associated specialties, affiliations and a list of published articles.
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34
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1357
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Recent Articles
1.
Portela M, Mukherjee S, Paul S, La Marca J, Parsons L, Veraksa A, et al.
J Cell Sci
. 2024 Jan;
137(4).
PMID: 38240353
The tumour suppressor, Lethal (2) giant larvae [Lgl; also known as L(2)gl], is an evolutionarily conserved protein that was discovered in the vinegar fly Drosophila, where its depletion results in...
2.
Shrivastava R, Poxon R, Rottinghaus E, Essop L, Sanon V, Chipeta Z, et al.
BMC Health Serv Res
. 2021 Jan;
21(1):22.
PMID: 33407442
Background: In sub-Saharan Africa, there is dearth of trained laboratorians and strengthened laboratory systems to provide adequate and quality laboratory services for enhanced HIV control. In response to this challenge,...
3.
Kannangara J, Henstridge M, Parsons L, Kondo S, Mirth C, Warr C
Genetics
. 2020 Jul;
216(1):135-144.
PMID: 32675276
As juvenile animals grow, their behavior, physiology, and development need to be matched to environmental conditions to ensure they survive to adulthood. However, we know little about how behavior and...
4.
Zaytseva O, Mitchell N, Guo L, Marshall O, Parsons L, Hannan R, et al.
Development
. 2020 Jun;
147(11).
PMID: 32527935
Here, we report novel tumour suppressor activity for the Argonaute family RNA-binding protein AGO1, a component of the miRNA-dependent RNA-induced silencing complex (RISC). The mechanism for growth inhibition does not,...
5.
Warr C, Shaw K, Azim A, Piper M, Parsons L
Int J Mol Sci
. 2018 Dec;
19(12).
PMID: 30567377
Many of the links between diet and cancer are controversial and over simplified. To date, human epidemiological studies consistently reveal that patients who suffer diet-related obesity and/or type II diabetes...
6.
Portela M, Yang L, Paul S, Li X, Veraksa A, Parsons L, et al.
Sci Signal
. 2018 Jun;
11(533).
PMID: 29871910
Epithelial cell polarity is linked to the control of tissue growth and tumorigenesis. The tumor suppressor and cell polarity protein lethal-2-giant larvae (Lgl) promotes Hippo signaling and inhibits Notch signaling...
7.
Daniel S, Russ A, Guthridge K, Raina A, Estes P, Parsons L, et al.
Biol Open
. 2018 Jan;
7(1).
PMID: 29361610
() encodes a conserved tumor suppressor with established roles in cell polarity, asymmetric division, and proliferation control. Lgl's human orthologs, HUGL1 and HUGL2, are altered in human cancers, however, its...
8.
Parsons L, Somoskovi A, Lee E, Paramasivan C, Schneidman M, Birx D, et al.
Afr J Lab Med
. 2017 Oct;
1(1):11.
PMID: 29062731
Laboratory systems worldwide are challenged not only by the need to compete for scarce resources with other sections of national health care programmes, but also with the lack of understanding...
9.
Parsons L, Grzeschik N, Amaratunga K, Burke P, Quinn L, Richardson H
G3 (Bethesda)
. 2017 Jun;
7(8):2497-2509.
PMID: 28611255
In both and mammalian systems, epithelial structure and underlying cell polarity are essential for proper tissue morphogenesis and organ growth. Cell polarity interfaces with multiple cellular processes that are regulated...
10.
Lee J, Mitchell N, Zaytseva O, Chahal A, Mendis P, Cartier-Michaud A, et al.
Nat Commun
. 2015 Jun;
6:7404.
PMID: 26074141
Nucleotide excision DNA repair (NER) pathway mutations cause neurodegenerative and progeroid disorders (xeroderma pigmentosum (XP), Cockayne syndrome (CS) and trichothiodystrophy (TTD)), which are inexplicably associated with (XP) or without (CS/TTD)...