Lilith Reeves
Overview
Explore the profile of Lilith Reeves including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
257
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0
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Recent Articles
1.
Arumugam P, Carey B, Wikenheiser-Brokamp K, Krischer J, Wessendarp M, Shima K, et al.
Mol Ther Methods Clin Dev
. 2024 Apr;
32(2):101213.
PMID: 38596536
Pulmonary macrophage transplantation (PMT) is a gene and cell transplantation approach in development as therapy for hereditary pulmonary alveolar proteinosis (hPAP), a surfactant accumulation disorder caused by mutations in (and...
2.
Kohn D, Booth C, Shaw K, Xu-Bayford J, Garabedian E, Trevisan V, et al.
N Engl J Med
. 2021 May;
384(21):2002-2013.
PMID: 33974366
Background: Severe combined immunodeficiency due to adenosine deaminase (ADA) deficiency (ADA-SCID) is a rare and life-threatening primary immunodeficiency. Methods: We treated 50 patients with ADA-SCID (30 in the United States...
3.
Orschell C, Skaar T, DeFord M, Ybe J, Driscol J, Drury C, et al.
J Clin Transl Sci
. 2021 May;
5(1):e33.
PMID: 33948256
Introduction: Access to cutting-edge technologies is essential for investigators to advance translational research. The Indiana Clinical and Translational Sciences Institute (CTSI) spans three major and preeminent universities, four large academic...
4.
Tinch S, Szczur K, Swaney W, Reeves L, Witting S
Methods Mol Biol
. 2019 Feb;
1937:135-153.
PMID: 30706394
Lentiviral vectors have rapidly become a favorite tool for research and clinical gene transfer applications which seek to permanently introduce alterations in the genome. This status can be attributed primarily...
5.
Urbinati F, Wherley J, Geiger S, Campo Fernandez B, Kaufman M, Cooper A, et al.
Cytotherapy
. 2017 Jul;
19(9):1096-1112.
PMID: 28733131
Background Aims: Gene therapy by autologous hematopoietic stem cell transplantation (HSCT) represents a new approach to treat sickle cell disease (SCD). Optimization of the manufacture, characterization and testing of the...
6.
Reeves L, Dunn-Jensen L, Baldwin T, Tatikonda M, Cornetta K
Clin Transl Sci
. 2013 Aug;
6(4):297-302.
PMID: 23919365
Biomedical research enterprises require a large number of core facilities and resources to supply the infrastructure necessary for translational research. Maintaining the financial viability and promoting efficiency in an academic...
7.
Boeke A, Doumas P, Reeves L, McClurg K, Bischof D, Sego L, et al.
Hum Gene Ther Methods
. 2013 Jan;
24(1):49-57.
PMID: 23360377
Generating gene and cell therapy products under good manufacturing practices is a complex process. When determining the cost of these products, researchers must consider the large number of supplies used...
8.
Balcik B, Grassman E, Reeves L
Methods Mol Biol
. 2008 Dec;
506:467-76.
PMID: 19110645
Murine safety studies are routinely used for gathering preclinical safety and efficacy data and, for Phase I studies, Good Laboratory Practice (GLP) compliance is not mandated. However, extensive amounts of...
9.
Schuesler T, Reeves L, von Kalle C, Grassman E
Methods Mol Biol
. 2008 Dec;
506:281-98.
PMID: 19110633
Human gene transfer with gammaretroviral, murine leukemia virus (MLV) based vectors has been shown to effectively insert and express transgene sequences at a level of therapeutic benefit. However, there are...
10.
Nordling D, Kaiser A, Reeves L
Methods Mol Biol
. 2008 Dec;
506:265-79.
PMID: 19110632
This chapter will review the design and execution of release testing requirements for retroviral vectors and gene-modified cells consistent with ensuring the success of the clinical trial on the basis...