Liliane Fossati-Jimack
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Explore the profile of Liliane Fossati-Jimack including associated specialties, affiliations and a list of published articles.
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1094
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Recent Articles
1.
Corsiero E, Caliste M, Jagemann L, Fossati-Jimack L, Goldmann K, Cubuk C, et al.
J Clin Invest
. 2024 Jul;
134(12).
PMID: 38950333
Ectopic lymphoid structures (ELSs) in the rheumatoid synovial joints sustain autoreactivity against locally expressed autoantigens. We recently identified recombinant monoclonal antibodies (RA-rmAbs) derived from single, locally differentiated rheumatoid arthritis (RA)...
2.
Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, et al.
EMBO Rep
. 2024 Jun;
25(9):3842-3869.
PMID: 38918502
Cellular senescence is a hallmark of advanced age and a major instigator of numerous inflammatory pathologies. While endothelial cell (EC) senescence is aligned with defective vascular functionality, its impact on...
3.
Cubuk C, Lau R, Cutillas P, Rajeeve V, John C, Surace A, et al.
Arthritis Res Ther
. 2024 Jun;
26(1):120.
PMID: 38867295
Background: Kinases are intracellular signalling mediators and key to sustaining the inflammatory process in rheumatoid arthritis (RA). Oral inhibitors of Janus Kinase family (JAKs) are widely used in RA, while...
4.
Boutet M, Nerviani A, Fossati-Jimack L, Hands-Greenwood R, Ahmed M, Rivellese F, et al.
Osteoarthritis Cartilage
. 2023 Nov;
32(2):166-176.
PMID: 37984558
Objectives: Osteoarthritis (OA) is a debilitating and heterogeneous condition, characterized by various levels of articular cartilage degradation, osteophytes formation, and synovial inflammation. Multiple evidences suggest that synovitis may appear early...
5.
El Shikh M, El Sayed R, Aly N, Prediletto E, Hands R, Fossati-Jimack L, et al.
Front Med (Lausanne)
. 2022 Dec;
9:1013660.
PMID: 36465908
Follicular dendritic cells (FDCs) fundamentally contribute to the formation of synovial ectopic lymphoid-like structures in rheumatoid arthritis (RA) which is associated with poor clinical prognosis. Despite this critical role, regulation...
6.
Rivellese F, Surace A, Goldmann K, Sciacca E, Cubuk C, Giorli G, et al.
Nat Med
. 2022 May;
28(6):1256-1268.
PMID: 35589854
Patients with rheumatoid arthritis (RA) receive highly targeted biologic therapies without previous knowledge of target expression levels in the diseased tissue. Approximately 40% of patients do not respond to individual...
7.
Pontarini E, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Fossati-Jimack L, et al.
Front Immunol
. 2021 Oct;
12:706737.
PMID: 34594326
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease resulting from the inflammatory infiltration of exocrine glands, mainly salivary and lacrimal glands, leading to secretory dysfunction and serious complications including...
8.
Ferrari M, Onuoha S, Fossati-Jimack L, Nerviani A, Alves P, Pagani S, et al.
Front Immunol
. 2021 Mar;
12:640070.
PMID: 33679801
Biologic drugs, especially anti-TNF, are considered as the gold standard therapy in rheumatoid arthritis. However, non-uniform efficacy, incidence of infections, and high costs are major concerns. Novel tissue-specific agents may...
9.
Pontarini E, Murray-Brown W, Croia C, Lucchesi D, Conway J, Rivellese F, et al.
Ann Rheum Dis
. 2020 Sep;
79(12):1588-1599.
PMID: 32963045
Objectives: To explore the relevance of T-follicular-helper (Tfh) and pathogenic peripheral-helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa-associated lymphoid tissue (MALT) lymphomas (MALT-L) in Sjögren's syndrome...
10.
Jackson W, Gulino A, Fossati-Jimack L, Castro Seoane R, Tian K, Best K, et al.
J Invest Dermatol
. 2020 Jul;
141(2):404-414.e6.
PMID: 32682912
Nonmelanoma skin cancer such as cutaneous squamous cell carcinoma (cSCC) is the most common form of cancer and can occur as a consequence of DNA damage to the epithelium by...