Marina Botto
Overview
Explore the profile of Marina Botto including associated specialties, affiliations and a list of published articles.
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134
Citations
6667
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Recent Articles
1.
Malamud M, Whitehead L, McIntosh A, Colella F, Roelofs A, Kusakabe T, et al.
Nature
. 2024 Aug;
633(8029):442-450.
PMID: 39143217
Regulation of neutrophil activation is critical for disease control. Neutrophil extracellular traps (NETs), which are web-like structures composed of DNA and neutrophil-derived proteins, are formed following pro-inflammatory signals; however, if...
2.
Pickering M, Botto M
Eur J Immunol
. 2024 Apr;
54(7):e2350918.
PMID: 38629181
For many years complement activation in systemic lupus erythematosus (SLE) was viewed as a major cause of tissue injury. However, human and murine studies showed that complement plays a protective...
3.
Jackson W, Giacomassi C, Ward S, Owen A, Luis T, Spear S, et al.
Elife
. 2023 Aug;
12.
PMID: 37566453
Monocytes are heterogeneous innate effector leukocytes generated in the bone marrow and released into circulation in a CCR2-dependent manner. During infection or inflammation, myelopoiesis is modulated to rapidly meet the...
4.
Gisby J, Buang N, Papadaki A, Clarke C, Malik T, Medjeral-Thomas N, et al.
Nat Commun
. 2022 Dec;
13(1):7775.
PMID: 36522333
Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. Here, we perform longitudinal blood sampling of ESKD haemodialysis patients with COVID-19, collecting samples pre-infection, serially during...
5.
McDonnell T, Amarnani R, Spicer C, Jbari H, Pericleous C, Spiteri V, et al.
Lupus Sci Med
. 2022 Aug;
9(1).
PMID: 36007979
Objectives: The significance of antibodies directed against activated factor X (FXa) and thrombin (Thr) in patients with SLE and/or antiphospholipid syndrome (APS) is unknown. FXa and Thr are coregulated by...
6.
Belmonte B, Mangogna A, Gulino A, Cancila V, Morello G, Agostinis C, et al.
Front Immunol
. 2022 Jun;
13:882298.
PMID: 35711467
Pre-eclampsia is a pregnancy complication characterized by defective vascular remodeling in maternal decidua responsible for reduced blood flow leading to functional and structural alterations in the placenta. We have investigated...
7.
Zhou L, Kong G, Palmisano I, Cencioni M, Danzi M, De Virgiliis F, et al.
Science
. 2022 May;
376(6594):eabd5926.
PMID: 35549409
Aging is associated with increased prevalence of axonal injuries characterized by poor regeneration and disability. However, the underlying mechanisms remain unclear. In our experiments, RNA sequencing of sciatic dorsal root...
8.
Chan D, Bennett P, Lee Y, Kundu S, Teoh T, Adan M, et al.
Nat Commun
. 2022 Feb;
13(1):975.
PMID: 35190561
There has been a surge in studies implicating a role of vaginal microbiota in spontaneous preterm birth (sPTB), but most are associative without mechanistic insight. Here we show a comprehensive...
9.
Gilmore A, Wilson H, Cairns T, Botto M, Lightstone L, Bruce I, et al.
Lupus Sci Med
. 2022 Jan;
9(1).
PMID: 35074933
Objective: To explore the utility of the NanoString platform in elucidating kidney immune transcripts for class III, IV and V lupus nephritis (LN) using a retrospective cohort of formalin-fixed paraffin-embedded...
10.
Medjeral-Thomas N, Troldborg A, Hansen A, Pihl R, Clarke C, Peters J, et al.
Oxf Open Immunol
. 2021 Aug;
2(1):iqab014.
PMID: 34458849
Protease inhibitors influence a range of innate immunity and inflammatory pathways. We quantified plasma concentrations of key anti-inflammatory protease inhibitors in chronic haemodialysis patients with coronavirus disease 2019 (COVID-19). The...