Lijin Dong
Overview
Explore the profile of Lijin Dong including associated specialties, affiliations and a list of published articles.
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69
Citations
1719
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Recent Articles
1.
Bernardo-Colon A, Dong L, Abu-Asab M, Becerra S
Adv Exp Med Biol
. 2025 Feb;
1468:241-246.
PMID: 39930203
Photoreceptor cells express the patatin-like phospholipase domain-containing 2 (PNPLA2) gene that codes for pigment epithelium-derived factor receptor (PEDF-R). PEDF-R exhibits phospholipase activity that mediates the neurotrophic action of its ligand...
2.
Dey P, Singh N, Zelinger L, Batz Z, Nellissery J, White Carreiro N, et al.
Hum Mol Genet
. 2024 Nov;
34(1):64-76.
PMID: 39532089
Genome-wide association studies have uncovered mostly non-coding variants at over 60 genetic loci linked to susceptibility for age-related macular degeneration (AMD). To ascertain the causal gene at the PILRB/PILRA locus,...
3.
Lee H, Fenollar-Ferrer C, Isgrig K, Wang Y, Valente K, Eide J, et al.
Sci Adv
. 2024 Oct;
10(41):eadm8663.
PMID: 39383236
Decreased presence or activity of human SLC26A4 at the plasma membrane is a common cause of hearing loss. SLC26A4 (Pendrin) is necessary for normal reabsorption of endolymph, the fluid bathing...
4.
Wang G, Peng S, Reyes Mendez M, Keramidas A, Castellano D, Wu K, et al.
Cell
. 2024 Oct;
187(23):6649-6668.e35.
PMID: 39357522
Alcohol is the most consumed and abused psychoactive drug globally, but the molecular mechanisms driving alcohol action and its associated behaviors in the brain remain enigmatic. Here, we have discovered...
5.
Pandey S, Han W, Li J, Shepard R, Wu K, Castellano D, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(31):e2400078121.
PMID: 39058580
Current treatments of anxiety and depressive disorders are plagued by considerable side effects and limited efficacies, underscoring the need for additional molecular targets that can be leveraged to improve medications....
6.
Liu J, He Y, Lwin C, Han M, Guan B, Naik A, et al.
Brain
. 2024 May;
147(6):2085-2097.
PMID: 38735647
Biallelic pathogenic variants in the PNPLA6 gene cause a broad spectrum of disorders leading to gait disturbance, visual impairment, anterior hypopituitarism and hair anomalies. PNPLA6 encodes neuropathy target esterase (NTE),...
7.
Pickles S, Zanetti Alepuz D, Koike Y, Yue M, Tong J, Liu P, et al.
Front Cell Dev Biol
. 2023 Aug;
11:1251551.
PMID: 37614226
Treatments for neurodegenerative disease, including Frontotemporal dementia (FTD) and Amyotrophic lateral sclerosis (ALS), remain rather limited, underscoring the need for greater mechanistic insight and disease-relevant models. Our ability to develop...
8.
Boudkkazi S, Schwenk J, Nakaya N, Brechet A, Kollewe A, Harada H, et al.
Neuron
. 2023 Aug;
111(16):2544-2556.e9.
PMID: 37591201
Information processing and storage in the brain rely on AMPA-receptors (AMPARs) and their context-dependent dynamics in synapses and extra-synaptic sites. We found that distribution and dynamics of AMPARs in the...
9.
Liu J, He Y, Lwin C, Han M, Guan B, Naik A, et al.
bioRxiv
. 2023 Jun;
PMID: 37333224
Biallelic pathogenic variants in the gene cause a broad spectrum of disorders leading to gait disturbance, visual impairment, anterior hypopituitarism, and hair anomalies. encodes Neuropathy target esterase (NTE), yet the...
10.
Bernardo-Colon A, Dong L, Abu-Asab M, Brush R, Agbaga M, Becerra S
J Lipid Res
. 2023 Mar;
64(5):100358.
PMID: 36934843
Photoreceptor cells express the patatin-like phospholipase domain-containing 2 (PNPLA2) gene that codes for pigment epithelium-derived factor receptor (PEDF-R) (also known as ATGL). PEDF-R exhibits phospholipase activity that mediates the neurotrophic...