Liangqi Xie
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Explore the profile of Liangqi Xie including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
969
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Recent Articles
1.
Dong P, Zhang S, Gandin V, Xie L, Wang L, Lemire A, et al.
Nat Genet
. 2024 Jul;
56(8):1654-1664.
PMID: 39048795
The contrast between the disruption of genome topology after cohesin loss and the lack of downstream gene expression changes instigates intense debates regarding the structure-function relationship between genome and gene...
2.
Xie L, Hu M, Gan Y, Ru Y, Xiao B, Jin X, et al.
J Ethnopharmacol
. 2024 Jul;
334:118587.
PMID: 39025160
Ethnopharmacological Relevance: jinkui Shenqi Pill (JSP) is a classic traditional Chinese medicine used to treat "Kidney Yang Deficiency" disease. Previous studies indicate a protective effect of JSP on apoptosis in...
3.
Holland K, Plutkis S, Daugird T, Sau A, Grimm J, English B, et al.
bioRxiv
. 2024 May;
PMID: 38766149
Spontaneously blinking fluorophores permit the detection and localization of individual molecules without reducing buffers or caging groups, thus simplifying single-molecule localization microscopy (SMLM). The intrinsic blinking properties of such dyes...
4.
Zheng D, Elnegiry A, Luo C, Bendahou M, Xie L, Bell D, et al.
Life Sci Alliance
. 2024 May;
7(7).
PMID: 38724194
NUT carcinoma (NC) is an aggressive cancer with no effective treatment. About 70% of NUT carcinoma is associated with chromosome translocation events that lead to the formation of a fusion...
5.
Huang H, Shah H, Hao J, Lin J, Prayson R, Xie L, et al.
Neuro Oncol
. 2024 Mar;
26(8):1388-1401.
PMID: 38456228
Background: Hypoxia is associated with poor prognosis in many cancers including glioblastoma (GBM). Glioma stem-like cells (GSCs) often reside in hypoxic regions and serve as reservoirs for disease progression. Long...
6.
Lee L, Yu H, Jia B, Jussila A, Zhu C, Chen J, et al.
Nat Commun
. 2023 Aug;
14(1):4873.
PMID: 37573342
Multiplexed DNA fluorescence in situ hybridization (FISH) imaging technologies have been developed to map the folding of chromatin fibers at tens of nanometers and up to several kilobases in resolution...
7.
Wang X, Yang C, Li Y, Gong Q, Ru Y, Xie L, et al.
Int J Dev Neurosci
. 2023 May;
83(5):417-430.
PMID: 37211717
Neural tube defects (NTDs) are severe congenital malformations that can lead to lifelong disability. Wuzi Yanzong Pill (WYP) is an herbal formula of traditional Chinese medicine (TCM) that has been...
8.
Wang X, Yang C, Ru Y, Xie L, Xiao B, Jin X, et al.
J Ethnopharmacol
. 2023 Apr;
313:116540.
PMID: 37088238
Ethnopharmacological Relevance: Wuzi Yanzong Pill (WYP) is a classic traditional Chinese medicine (TCM) formula that is used for reproductive system diseases. Previous studies showed that WYP had a preventive effect...
9.
Lange J, Rose J, Chen C, Pichugin Y, Xie L, Tang J, et al.
Nat Genet
. 2022 Sep;
54(10):1527-1533.
PMID: 36123406
Oncogene amplification on extrachromosomal DNA (ecDNA) is a common event, driving aggressive tumor growth, drug resistance and shorter survival. Currently, the impact of nonchromosomal oncogene inheritance-random identity by descent-is poorly...
10.
Xie L, Dong P, Qi Y, Hsieh T, English B, Jung S, et al.
Nat Genet
. 2022 Apr;
54(4):481-491.
PMID: 35410381
Mammalian chromosomes are organized into megabase-sized compartments that are further subdivided into topologically associating domains (TADs). While the formation of TADs is dependent on cohesin, the mechanism behind compartmentalization remains...