Timothy A Brown
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Explore the profile of Timothy A Brown including associated specialties, affiliations and a list of published articles.
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124
Citations
4156
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Recent Articles
1.
Holland K, Plutkis S, Daugird T, Sau A, Grimm J, English B, et al.
bioRxiv
. 2024 May;
PMID: 38766149
Spontaneously blinking fluorophores permit the detection and localization of individual molecules without reducing buffers or caging groups, thus simplifying single-molecule localization microscopy (SMLM). The intrinsic blinking properties of such dyes...
2.
Jradi F, English B, Brown T, Aaron J, Khuon S, Galbraith J, et al.
bioRxiv
. 2024 May;
PMID: 38766036
Single-molecule localization microscopy (SMLM) uses activatable or switchable fluorophores to create non-diffraction limited maps of molecular location in biological samples. Despite the utility of this imaging technique, the portfolio of...
3.
Marvin J, Kokotos A, Kumar M, Pulido C, Tkachuk A, Yao J, et al.
Proc Natl Acad Sci U S A
. 2024 May;
121(21):e2314604121.
PMID: 38748581
We developed a significantly improved genetically encoded quantitative adenosine triphosphate (ATP) sensor to provide real-time dynamics of ATP levels in subcellular compartments. iATPSnFR2 is a variant of iATPSnFR1, a previously...
4.
Farrell R, Bredvik K, Hoppa M, Hennigan S, Brown T, Ryan T
bioRxiv
. 2024 Feb;
PMID: 38405980
The endoplasmic reticulum (ER) is an important regulator of in cells and dysregulation of ER calcium homeostasis can lead to numerous pathologies. Understanding how various pharmacological and genetic perturbations of...
5.
Davidsen K, Marvin J, Aggarwal A, Brown T, Sullivan L
Elife
. 2024 Feb;
12.
PMID: 38393319
Intracellular levels of the amino acid aspartate are responsive to changes in metabolism in mammalian cells and can correspondingly alter cell function, highlighting the need for robust tools to measure...
6.
Galiano C, Andrea A, Tung E, Brown T, Rosellini A
Psychol Assess
. 2024 Jan;
36(3):192-199.
PMID: 38206840
The factor structure, reliability, and concurrent validity of the Distress Tolerance Scale were evaluated in a large outpatient sample ( = 775). Prior research demonstrates mixed findings regarding the most...
7.
Grimm J, Tkachuk A, Patel R, Hennigan S, Gutu A, Dong P, et al.
J Am Chem Soc
. 2023 Oct;
145(42):23000-23013.
PMID: 37842926
Rhodamine dyes are excellent scaffolds for developing a broad range of fluorescent probes. A key property of rhodamines is their equilibrium between a colorless lactone and fluorescent zwitterion. Tuning the...
8.
Beck J, Bowen M, Majeed R, Free B, Brown T, Brown B, et al.
J Dual Diagn
. 2023 Oct;
19(4):240-247.
PMID: 37813696
Objective: The current study examined associations of symptoms of posttraumatic stress disorder [PTSD], depression, and generalized anxiety disorder [GAD] with alcohol consumption and drinking to cope in a sample of...
9.
Davidsen K, Marvin J, Aggarwal A, Brown T, Sullivan L
bioRxiv
. 2023 Jul;
PMID: 37425831
Intracellular levels of the amino acid aspartate are responsive to changes in metabolism in mammalian cells and can correspondingly alter cell function, highlighting the need for robust tools to measure...
10.
Galiano C, Andrea A, Brown T, Rosellini A
Cognit Ther Res
. 2023 May;
47(3):327-339.
PMID: 37168695
Purpose: The present study examined the prospective direct and interactive effects of personality (neuroticism, extraversion) and experiencing changes in friendships during the pandemic on symptoms of stress, anxiety, and depression....