Lexing Yu
Overview
Explore the profile of Lexing Yu including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
889
Followers
0
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Related Specialties
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Top 10 Co-Authors
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Recent Articles
1.
Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, et al.
Cancer Cell
. 2021 Jun;
39(6):883.
PMID: 34129825
No abstract available.
2.
Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, et al.
Cancer Cell
. 2021 Apr;
39(6):866-882.e11.
PMID: 33930309
Cancer-associated fibroblasts (CAF) are a poorly characterized cell population in the context of liver cancer. Our study investigates CAF functions in intrahepatic cholangiocarcinoma (ICC), a highly desmoplastic liver tumor. Genetic...
3.
Tang J, Yan Z, Feng Q, Yu L, Wang H
Front Immunol
. 2021 Mar;
12:625472.
PMID: 33763069
Neutrophils are the largest population of circulating leukocytes and the first responder against invading pathogens or other danger signals. Sophisticated machineries help them play critical roles in immunity and inflammation,...
4.
Fang T, Lv H, Lv G, Li T, Wang C, Han Q, et al.
Nat Commun
. 2018 Jan;
9(1):191.
PMID: 29335551
The communication between tumor-derived elements and stroma in the metastatic niche has a critical role in facilitating cancer metastasis. Yet, the mechanisms tumor cells use to control metastatic niche formation...
5.
Caviglia J, Yan J, Jang M, Gwak G, Affo S, Yu L, et al.
Hepatology
. 2017 Nov;
67(6):2414-2429.
PMID: 29091291
Conclusion: Genetic and pharmacologic manipulation of miR-21 does not inhibit the development of liver fibrosis and liver cancer. Moreover, suppression of microRNA synthesis does not significantly affect HSC phenotype and...
6.
Su B, Luo T, Zhu J, Fu J, Zhao X, Chen L, et al.
Hepatology
. 2014 Oct;
61(2):585-97.
PMID: 25294684
Unlabelled: Hepatocellular carcinoma (HCC) is a prototype of inflammation-associated cancer. Oncoprotein Gankyrin, which mostly increases in HCC, plays a critical role in HCC development and metastasis. However, the exact mechanism...
7.
Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, et al.
Clin Cancer Res
. 2013 Aug;
19(19):5372-80.
PMID: 23942093
Purpose: The AMP-activated protein kinase (AMPK) serves as an energy sensor in eukaryotic cells and occupies a central role in linking metabolism and cancer development. However, the phosphorylation status of...
8.
Dai R, Li J, Fu J, Chen Y, Yu L, Zhao X, et al.
J Biol Chem
. 2012 Mar;
287(18):14586-97.
PMID: 22418436
c-Met, the tyrosine-kinase receptor for hepatocyte growth factor, plays a critical role in the tumorigenesis of hepatocellular carcinoma (HCC). However, the underlying mechanism remains incompletely understood. The mature c-Met protein...