Leslie A Mangold
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Explore the profile of Leslie A Mangold including associated specialties, affiliations and a list of published articles.
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48
Citations
1871
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Recent Articles
1.
Shrestha E, White J, Yu S, Kulac I, Ertunc O, De Marzo A, et al.
J Urol
. 2017 Aug;
199(1):161-171.
PMID: 28797714
Purpose: Studies demonstrating bacterial DNA and cultivable bacteria in urine samples have challenged the clinical dogma that urine is sterile. Furthermore, studies now indicate that dysbiosis of the urinary microbiome...
2.
Partin A, Van Neste L, Klein E, Marks L, Gee J, Troyer D, et al.
J Urol
. 2014 Apr;
192(4):1081-7.
PMID: 24747657
Purpose: The DOCUMENT multicenter trial in the United States validated the performance of an epigenetic test as an independent predictor of prostate cancer risk to guide decision making for repeat...
3.
Rosenbaum E, Begum S, Brait M, Zahurak M, Maldonado L, Mangold L, et al.
Prostate
. 2011 Dec;
72(10):1133-9.
PMID: 22127895
Purpose: To evaluate the prognostic significance of six epigenetic biomarkers (AIM1, CDH1, KIF1A, MT1G, PAK3, and RBM6 promoter hypermethlation) in a homogeneous group of prostate cancer patients, following radical prostatectomy...
4.
Trock B, Brotzman M, Mangold L, Bigley J, Epstein J, McLeod D, et al.
BJU Int
. 2011 Nov;
110(1):56-62.
PMID: 22077694
Unlabelled: Study Type - Diagnostic (exploratory cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Hypermethylation of genes such as glutathione-S-transferase P1 (GSTP1)...
5.
Terada N, Shiraishi T, Zeng Y, Mooney S, Yeater D, Mangold L, et al.
Prostate
. 2011 Oct;
72(9):966-76.
PMID: 22025384
Background: Cysteine-rich angiogenic inducer 61 (Cyr61) is an extracellular matrix protein involved in the transduction of growth factor and hormone signaling. Previously, we demonstrated that Cyr61 was highly expressed in...
6.
Jain A, McKnight D, Fisher L, Humphreys E, Mangold L, Partin A, et al.
Clin Cancer Res
. 2009 Aug;
15(16):5199-207.
PMID: 19671866
Purpose: The small integrin-binding ligand N-linked glycoprotein (SIBLING) gene family includes bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP), matrix extracellular phosphoglycoprotein (MEPE), and osteopontin (OPN). Previous...
7.
Isharwal S, Miller M, Epstein J, Mangold L, Humphreys E, Partin A, et al.
Urology
. 2009 Feb;
73(5):1092-7.
PMID: 19193410
Objectives: Transformation of normal epithelium into cancer cells involves epigenetic and genetic changes and modifications in nuclear structure and tissue architecture. To evaluate nuclear morphometric alterations and clinicopathologic features for...
8.
Hernandez D, Han M, Humphreys E, Mangold L, Taneja S, Childs S, et al.
BJU Int
. 2008 Nov;
103(5):609-14.
PMID: 19007374
Objectives: To develop a logistic regression-based model to predict prostate cancer biopsy at, and compare its performance to the risk calculator developed by the Prostate Cancer Prevention Trial (PCPT), which...
9.
Fujita K, Ewing C, Chan D, Mangold L, Partin A, Isaacs W, et al.
Int J Cancer
. 2008 Nov;
124(3):664-9.
PMID: 19004009
We have previously shown that endoglin (CD105) is upregulated in prostatic fluid of men with large volume prostate cancer. We chose to assess endoglin levels in urine and serum from...
10.
Isharwal S, Miller M, Epstein J, Mangold L, Humphreys E, Partin A, et al.
Int J Cancer
. 2008 Sep;
123(11):2636-43.
PMID: 18767043
Abnormal DNA content in tumor cells represents large scale chromosomal alterations and reflects later changes of genetic instability. Her-2/neu oncogene is amplified in 20-30% of breast and ovarian cancer patients...