Lesley M Chapman
Overview
Explore the profile of Lesley M Chapman including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
463
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0
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Recent Articles
1.
Schaffer A, Dominguez D, Chapman L, Gertz E, Budhu A, Forgues M, et al.
BMC Genomics
. 2021 Nov;
22(1):814.
PMID: 34763675
Background: Engineered versions of adeno-associated virus (AAV) are commonly used in gene therapy but evidence revealing a potential oncogenic role of natural AAV in hepatocellular carcinoma (HCC) has raised concerns....
2.
Chapman L, Spies N, Pai P, Lim C, Carroll A, Narzisi G, et al.
PLoS Comput Biol
. 2020 Jun;
16(6):e1007933.
PMID: 32559231
A high quality benchmark for small variants encompassing 88 to 90% of the reference genome has been developed for seven Genome in a Bottle (GIAB) reference samples. However a reliable...
3.
Chapman L, Ture S, Field D, Morrell C
Immunol Res
. 2017 Apr;
65(4):828-840.
PMID: 28378118
MicroRNAs (miRNAs) are major regulators of cell responses, particularly in stressed cell states and host immune responses. Some miRNAs have a role in pathogen defense, including regulation of immune responses...
4.
Morrell C, Aggrey A, Chapman L, Modjeski K
Blood
. 2014 Mar;
123(18):2759-67.
PMID: 24585776
Despite their small size and anucleate status, platelets have diverse roles in vascular biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also immune cells that...
5.
Chapman L, Aggrey A, Field D, Srivastava K, Ture S, Yui K, et al.
J Immunol
. 2012 Jun;
189(2):916-23.
PMID: 22706078
Platelets are most recognized for their vital role as the cellular mediator of thrombosis, but platelets also have important immune functions. Platelets initiate and sustain vascular inflammation in many disease...