Lesley C Dupuy
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Explore the profile of Lesley C Dupuy including associated specialties, affiliations and a list of published articles.
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24
Citations
368
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Recent Articles
11.
Bounds C, Terry F, Moise L, Hannaman D, Martin W, De Groot A, et al.
Hum Vaccin Immunother
. 2017 Jun;
13(12):2824-2836.
PMID: 28575582
Immunoinformatics tools were used to predict human leukocyte antigen (HLA) class II-restricted T cell epitopes within the envelope glycoproteins and nucleocapsid proteins of Ebola virus (EBOV) and Sudan virus (SUDV)...
12.
Hannaman D, Dupuy L, Ellefsen B, Schmaljohn C
Vaccine
. 2016 May;
34(31):3607-12.
PMID: 27206386
Venezuelan equine encephalitis virus (VEEV), a mosquito-borne alphavirus, causes periodic epizootics in equines and is a recognized biological defense threat for humans. There are currently no FDA-licensed vaccines against VEEV....
13.
Bounds C, Kwilas S, Kuehne A, Brannan J, Bakken R, Dye J, et al.
PLoS One
. 2015 Oct;
10(9):e0137786.
PMID: 26422247
DNA vaccination of transchromosomal bovines (TcBs) with DNA vaccines expressing the codon-optimized (co) glycoprotein (GP) genes of Ebola virus (EBOV) and Sudan virus (SUDV) produce fully human polyclonal antibodies (pAbs)...
14.
Grant-Klein R, Altamura L, Badger C, Bounds C, Van Deusen N, Kwilas S, et al.
Hum Vaccin Immunother
. 2015 May;
11(8):1991-2004.
PMID: 25996997
Cynomolgus macaques were vaccinated by intramuscular electroporation with DNA plasmids expressing codon-optimized glycoprotein (GP) genes of Ebola virus (EBOV) or Marburg virus (MARV) or a combination of codon-optimized GP DNA...
15.
Wolfe D, Heppner D, Gardner S, Jaing C, Dupuy L, Schmaljohn C, et al.
Am J Trop Med Hyg
. 2014 May;
91(3):442-50.
PMID: 24842880
Vaccinations against the encephalitic alphaviruses (western, eastern, and Venezuelan equine encephalitis virus) are of significant interest to biological defense, public health, and agricultural communities alike. Although vaccines licensed for veterinary...
16.
Grant-Klein R, Van Deusen N, Badger C, Hannaman D, Dupuy L, Schmaljohn C
Hum Vaccin Immunother
. 2012 Aug;
8(11):1703-6.
PMID: 22922764
We evaluated the immunogenicity and protective efficacy of DNA vaccines expressing the codon-optimized envelope glycoprotein genes of Zaire ebolavirus, Sudan ebolavirus, and Marburg marburgvirus (Musoke and Ravn). Intramuscular or intradermal...
17.
Dupuy L, Reed D
Curr Opin Virol
. 2012 Jun;
2(3):363-7.
PMID: 22709522
Venezuelan, western, and eastern equine encephalitis viruses are New World alphaviruses that are recognized as potential agents of biowarfare and bioterrorism owing to their morbidity and mortality in humans, ease...
18.
Koehler J, Dupuy L, Garrison A, Beitzel B, Richards M, Ripoll D, et al.
Antiviral Res
. 2011 Oct;
92(3):461-9.
PMID: 22020161
Type I interferons (IFNs) are potent mediators of the innate immune response to viral infection. IFNs released from infected cells bind to a receptor (IFNAR) on neighboring cells, triggering signaling...
19.
Dupuy L, Richards M, Ellefsen B, Chau L, Luxembourg A, Hannaman D, et al.
Clin Vaccine Immunol
. 2011 Apr;
18(5):707-16.
PMID: 21450977
We evaluated the immunogenicity and protective efficacy of a DNA vaccine expressing codon-optimized envelope glycoprotein genes of Venezuelan equine encephalitis virus (VEEV) when delivered by intramuscular electroporation. Mice vaccinated with...
20.
Dupuy L, Richards M, Reed D, Schmaljohn C
Vaccine
. 2010 Sep;
28(46):7345-50.
PMID: 20851089
A study to evaluate the immunogenicity and protective efficacy of a Venezuelan equine encephalitis virus (VEEV) DNA vaccine in an aerosol model of nonhuman primate infection was performed. Cynomolgus macaques...